Articles

Association of serum total bilirubin levels with diastolic dysfunction in heart failure with preserved ejection fraction

Left ventricular diastolic dysfunction is one of the main characteristics of heart failure patients with a preserved left ventricular ejection fraction. As bilirubin is regarded as an important endogenous anti...

Authors: Huan Zheng, Ye Li and Nanzi Xie

Acute oral toxicity and anti-inflammatory activity of hydroalcoholic extract from Lampaya medicinalis Phil in rats

Algesia and inflammation are related with several pathological conditions. It is known that many drugs available for the treatment of these problems cause unwanted side effects. This study was aimed at evaluat...

Authors: Glauco Morales, Adrián Paredes, Alberto Olivares and Jaime Bravo

Selected spices and their combination modulate hypercholesterolemia-induced oxidative stress in experimental rats

Effect of aqueous extracts of Allium sativum (garlic), Zingiber officinale (ginger), Capsicum fructensces (cayenne pepper) and their mixture on oxidative stress in rats fed high Cholesterol/high fat diet was inve...

Authors: Gloria A Otunola, Oyelola B Oloyede, Adenike T Oladiji and Anthony J Afolayan

Effects of R219K polymorphism of ATP-binding cassette transporter 1 gene on serum lipids ratios induced by a high-carbohydrate and low-fat diet in healthy youth

Diets are the important players in regulating plasma lipid profiles. And the R219K polymorphism at the gene of ATP-binding cassette transporter 1(ABCA1) was reported to be associated with the profiles. However, n...

Authors: Hui Liu, Jia Lin, Xing Chun Zhu, Yuan Hao Li, Mei Fan, Rong Rong Zhang and Ding Zhi Fang

Assessment of changes in the brca2 and p53 genes in breast invasive ductal carcinoma in northeast Brazil

BRCA protein interacts with at least 13 different proteins that have been implicated with cancer susceptibility and loss of BRCA function is correlated to sensitivity to DNA crosslinking agents in preclinical ...

Authors: Eduardo AVF Ramalho, João LQ Silva-Filho, Marina FS Cartaxo, Carmelita BL Cavalcanti, Moacyr JBM Rêgo, Maria BM Oliveira and Eduardo IC Beltrão

First report of in vitro selection of RNA aptamers targeted to recombinant Loxosceles laeta spider toxins

Loxoscelism is the envenomation caused by the bite of Loxosceles spp. spiders. It entails severe necrotizing skin lesions, sometimes accompanied by systemic reactions and even death. There are no diagnostic means...

Authors: Amalia Sapag, Catalina Salinas-Luypaert and Carlos Constenla-Muñoz

Biological Research marks its 50th year by joining BioMed Central

Authors: Manuel J Santos