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  1. Content type: Research article

    Chemokine (C-C motif) receptor 6 (CCR6) is present in sperm and plays a significant role in sperm motility and chemotaxis acting in the reproductive tracts. However, the expression and functional significance ...

    Authors: Ruiying Diao, Xueyong Cai, Lu Liu, Lihua Yang, YongGang Duan, Zhiming Cai, Yaoting Gui and Lisha Mou

    Citation: Biological Research 2018 51:12

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  2. Content type: Research article

    Gastric cancer occupies the fourth highest morbidity rate of cancers worldwide. Clinical therapies of gastric cancer remain limited because of uncertainty of mechanisms and shortness of effective medicine. Thu...

    Authors: Yu Li, Depeng Zhang, Kaikai Yu, Yudong Hu, Qiong Wu, Feng Qian and Zishu Wang

    Citation: Biological Research 2018 51:11

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  3. Content type: Research article

    Heat stress proteins are implicated in stabilizing and refolding denatured proteins in vertebrates and invertebrates. Members of the Hsp70 gene family comprise the cognate heat shock protein (Hsc70) and induci...

    Authors: Marcelo González-Aravena, Camila Calfio, Luis Mercado, Byron Morales-Lange, Jorn Bethke, Julien De Lorgeril and César A. Cárdenas

    Citation: Biological Research 2018 51:8

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  4. Content type: Research article

    Low phosphorus availability is a major factor restricting rice growth. Dongxiang wild rice (Oryza rufipogon Griff.) has many useful genes lacking in cultivated rice, including stress resistance to phosphorus defi...

    Authors: Qian-Wen Deng, Xiang-Dong Luo, Ya-Ling Chen, Yi Zhou, Fan-Tao Zhang, Biao-Lin Hu and Jian-Kun Xie

    Citation: Biological Research 2018 51:7

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  5. Content type: Research article

    Cocaine-and amphetamine regulated transcript (CART) is an endogenous neuropeptide, which is widespread in animals, plays a key role in regulation of follicular atresia in cattle and sheep. Among animal ovaries, C...

    Authors: Pengfei Li, Jinzhu Meng, Jiongjie Jing, Qingling Hao, Zhiwei Zhu, Jianbo Yao and Lihua Lyu

    Citation: Biological Research 2018 51:6

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  6. Content type: Research article

    Peroxisome proliferator activated receptor alpha (PPARα), a regulator of enzymes involved in β oxidation, has been reported to influence lymphocyte activation. The purpose of this study was to determine whethe...

    Authors: Ian N. Hines, Michael Kremer, Sherri M. Moore and Michael D. Wheeler

    Citation: Biological Research 2018 51:5

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  7. Content type: Review

    Aquaporins (AQP) are channel proteins belonging to the Major Intrinsic Protein (MIP) superfamily that play an important role in plant water relations. The main role of aquaporins in plants is transport of wate...

    Authors: Ranganathan Kapilan, Maryam Vaziri and Janusz J. Zwiazek

    Citation: Biological Research 2018 51:4

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  8. Content type: Research article

    The WNT pathway regulates intestinal stem cells and is frequently disrupted in intestinal adenomas. The pathway contains several potential biotargets for interference, including the poly-ADP ribosyltransferase...

    Authors: Jens Henrik Norum, Ellen Skarpen, Andreas Brech, Raoul Kuiper, Jo Waaler, Stefan Krauss and Therese Sørlie

    Citation: Biological Research 2018 51:3

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  9. Content type: Research article

    This study determined the regulatory effects of inducible T-cell co-stimulators (ICOS) in human hepatocellular carcinoma HepG2 cells using a RNA interference (RNAi) technique.

    Authors: Yaning Wei, Yanan Wang, Aimin Zang, Yanhong Shang, Zizheng Song, Zhiyu Wang, Yangyang Wang and Hua Yang

    Citation: Biological Research 2018 51:2

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  10. Content type: Research article

    Understanding the molecular basis underlying the formation of bone-forming osteocytes and lipid-storing adipocytes will help provide insights into the cause of disorders originating in stem/progenitor cells an...

    Authors: Alma Madrigal, Lun Tan and Yuanxiang Zhao

    Citation: Biological Research 2017 50:43

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  11. Content type: Research article

    Fresh frozen plasma (FFP) administration may increase the risk of nosocomial infections in parallel with the development of immune modulation. This could be driven by soluble mediators, possibly influencing th...

    Authors: Mariana Patlán, Fausto Sánchez-Muñoz, Luis M. Amezcua-Guerra, Adriana Granados, Araceli Páez, Felipe Massó, Ana M. Mejía, Angeles Soster, Rafael Bojalil, Lenin Pavón, Luis A. Jiménez-Zamudio and Ricardo Márquez-Velasco

    Citation: Biological Research 2017 50:42

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  12. Content type: Research article

    The marine environment is a rich source of bioactive natural products. Many of the marine bioactive compounds have been derived successfully from molluscs. Euchelus asper is a marine mollusc which is commonly fou...

    Authors: Sweta Agrawal, Sachin Chaugule, Shashank More, Gargi Rane and Madhavi Indap

    Citation: Biological Research 2017 50:41

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  13. Content type: Research article

    Programmed cell death 5 (PDCD5) is an apoptosis-related gene cloned from TF-1 cells whose primary biological functions are to promote apoptosis and immune regulation. The effects and mechanisms exerted by key ...

    Authors: Feng Yuan, Junfeng Wang, Keshi Zhang, Zhao Li and Zhenpeng Guan

    Citation: Biological Research 2017 50:40

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  14. Content type: Research article

    Ferredoxin NADP(H) oxidoreductases (EC 1.18.1.2) (FNR) are flavoenzymes present in photosynthetic organisms; they are relevant for the production of reduced donors to redox reactions, i.e. in photosynthesis, t...

    Authors: María Alejandra Vorphal, Carola Bruna, Traudy Wandersleben, Jorge Dagnino-Leone, Francisco Lobos-González, Elena Uribe, José Martínez-Oyanedel and Marta Bunster

    Citation: Biological Research 2017 50:39

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  15. Content type: Short report

    The nuclear architecture of meiotic prophase spermatocytes is based on higher-order patterns of spatial associations among chromosomal domains and consequently is prone to modification by chromosomal rearrange...

    Authors: Soledad Berríos, Raúl Fernández-Donoso and Eliana Ayarza

    Citation: Biological Research 2017 50:38

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  16. Content type: Review

    Breast cancer (BC) is the most common malignancy among women worldwide. A major advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and BRCA2 (BRCA1/2) genes, which are considere...

    Authors: Lilian Jara, Sebastian Morales, Tomas de Mayo, Patricio Gonzalez-Hormazabal, Valentina Carrasco and Raul Godoy

    Citation: Biological Research 2017 50:35

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  17. Content type: Review

    Breast cancer remains a worldwide public health dilemma and is currently the most common tumour in the globe. Awareness of breast cancer, public attentiveness, and advancement in breast imaging has made a posi...

    Authors: Muhammad Akram, Mehwish Iqbal, Muhammad Daniyal and Asmat Ullah Khan

    Citation: Biological Research 2017 50:33

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  18. Content type: Research article

    Growing evidence has supported that long non-coding RNAs (lncRNAs) could play vital roles in the development, progression, and prognosis of colorectal cancer (CRC). However, little is known about the clinical ...

    Authors: Xiaogang Shen, Yifeng Bai, Bin Luo and Xiaogang Zhou

    Citation: Biological Research 2017 50:32

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  19. Content type: Research article

    MiR-320 is downregulated in multiple cancers, including glioma and acts as tumor suppressor through inhibiting tumor cells proliferation and inducing apoptosis. PBX3 (Pre-B cell leukemia homeobox 3), a putativ...

    Authors: Cuicui Pan, Hua Gao, Ni Zheng, Qi Gao, Yuanquan Si and Yueran Zhao

    Citation: Biological Research 2017 50:31

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