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  1. Content type: Research article

    The marine environment is a rich source of bioactive natural products. Many of the marine bioactive compounds have been derived successfully from molluscs. Euchelus asper is a marine mollusc which is commonly fou...

    Authors: Sweta Agrawal, Sachin Chaugule, Shashank More, Gargi Rane and Madhavi Indap

    Citation: Biological Research 2017 50:41

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  2. Content type: Research article

    Programmed cell death 5 (PDCD5) is an apoptosis-related gene cloned from TF-1 cells whose primary biological functions are to promote apoptosis and immune regulation. The effects and mechanisms exerted by key ...

    Authors: Feng Yuan, Junfeng Wang, Keshi Zhang, Zhao Li and Zhenpeng Guan

    Citation: Biological Research 2017 50:40

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  3. Content type: Research article

    Ferredoxin NADP(H) oxidoreductases (EC 1.18.1.2) (FNR) are flavoenzymes present in photosynthetic organisms; they are relevant for the production of reduced donors to redox reactions, i.e. in photosynthesis, t...

    Authors: María Alejandra Vorphal, Carola Bruna, Traudy Wandersleben, Jorge Dagnino-Leone, Francisco Lobos-González, Elena Uribe, José Martínez-Oyanedel and Marta Bunster

    Citation: Biological Research 2017 50:39

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  4. Content type: Short report

    The nuclear architecture of meiotic prophase spermatocytes is based on higher-order patterns of spatial associations among chromosomal domains and consequently is prone to modification by chromosomal rearrange...

    Authors: Soledad Berríos, Raúl Fernández-Donoso and Eliana Ayarza

    Citation: Biological Research 2017 50:38

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  5. Content type: Review

    Breast cancer (BC) is the most common malignancy among women worldwide. A major advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and BRCA2 (BRCA1/2) genes, which are considere...

    Authors: Lilian Jara, Sebastian Morales, Tomas de Mayo, Patricio Gonzalez-Hormazabal, Valentina Carrasco and Raul Godoy

    Citation: Biological Research 2017 50:35

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  6. Content type: Review

    Breast cancer remains a worldwide public health dilemma and is currently the most common tumour in the globe. Awareness of breast cancer, public attentiveness, and advancement in breast imaging has made a posi...

    Authors: Muhammad Akram, Mehwish Iqbal, Muhammad Daniyal and Asmat Ullah Khan

    Citation: Biological Research 2017 50:33

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  7. Content type: Research article

    Growing evidence has supported that long non-coding RNAs (lncRNAs) could play vital roles in the development, progression, and prognosis of colorectal cancer (CRC). However, little is known about the clinical ...

    Authors: Xiaogang Shen, Yifeng Bai, Bin Luo and Xiaogang Zhou

    Citation: Biological Research 2017 50:32

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  8. Content type: Research article

    Porcine Deltacoronavirus (PDCoV) is a newly emerged enteropathogenic coronavirus that causes diarrhea and mortality in neonatal piglets. PDCoV has spread to many countries around the world, leading to significant...

    Authors: Fanfan Zhang, Yu Ye, Deping Song, Nannan Guo, Qi Peng, Anqi Li, Xingrong Zhou, Yanjun Chen, Min Zhang, Dongyan Huang and Yuxin Tang

    Citation: Biological Research 2017 50:30

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  9. Content type: Research article

    MiR-320 is downregulated in multiple cancers, including glioma and acts as tumor suppressor through inhibiting tumor cells proliferation and inducing apoptosis. PBX3 (Pre-B cell leukemia homeobox 3), a putativ...

    Authors: Cuicui Pan, Hua Gao, Ni Zheng, Qi Gao, Yuanquan Si and Yueran Zhao

    Citation: Biological Research 2017 50:31

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  10. Content type: Research article

    Obsessive–compulsive disorder (OCD) is a severe neuropsychiatric condition affecting 1–3% of the worldwide population. OCD has a strong genetic component, and the SLC1A1 gene that encodes neuronal glutamate trans...

    Authors: Luis F. González, Francisca Henríquez-Belmar, Claudia Delgado-Acevedo, Marisol Cisternas-Olmedo, Gloria Arriagada, Ramón Sotomayor-Zárate, Dennis L. Murphy and Pablo R. Moya

    Citation: Biological Research 2017 50:29

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  11. Content type: Research article

    The Tridax procumbens extracts (TPE) are known for their ethno-medicinal properties to increase osteogenic functioning in mesenchymal stem cells. Recently, we found that the T. procumbens flavonoids (TPF) signifi...

    Authors: Md. Abdullah Al Mamun, Mohammad Jakir Hosen, Amina Khatun, M. Masihul Alam and Md. Abdul Alim Al-Bari

    Citation: Biological Research 2017 50:28

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  12. Content type: Research article

    CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived...

    Authors: Li Zhang, Jinyun Tan, Xiaoping Jiang, Weiwei Qian, Ting Yang, Xijun Sun, Zhaohui Chen and Qiwen Zhu

    Citation: Biological Research 2017 50:26

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  13. Content type: Review

    Jojoba is considered a promising oil crop and is cultivated for diverse purposes in many countries. The jojoba seed produces unique high-quality oil with a wide range of applications such as medical and indust...

    Authors: Jameel R. Al-Obaidi, Mohammed Farouq Halabi, Nasser S. AlKhalifah, Shanavaskhan Asanar, Abdulrahman A. Al-Soqeer and M. F. Attia

    Citation: Biological Research 2017 50:25

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  14. Content type: Research article

    Airway remodeling is a key feature of asthma, characterized by increased proliferation of airway smooth muscle cells (ASMCs). S100A8 is a calcium-binding protein with a potential to regulate cell proliferation...

    Authors: Yu-Dong Xu, Yu Wang, Lei-Miao Yin, Ling-Ling Peng, Gyoung-Hee Park and Yong-Qing Yang

    Citation: Biological Research 2017 50:23

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  15. Content type: Research article

    Hypertrophic scarring (HS) is a severe disease, and results from unusual wound healing. Col1A1 could promote the hypertrophic scar formation, and the expression of Col1A1 in HS tissue was markedly higher than ...

    Authors: Sheng Bi, Linlin Chai, Xi Yuan, Chuan Cao and Shirong Li

    Citation: Biological Research 2017 50:22

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  16. Content type: Research article

    Multiple techniques exist for detecting Mycobacteria, each having its own advantages and drawbacks. Among them, automated culture-based systems like the BACTEC-MGIT™ are popular because they are inexpensive, reli...

    Authors: Roli Kargupta, Sachidevi Puttaswamy, Aiden J. Lee, Timothy E. Butler, Zhongyu Li, Sounak Chakraborty and Shramik Sengupta

    Citation: Biological Research 2017 50:21

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  17. Content type: Short report

    Vegetative propagation of Fragaria sp. is traditionally carried out using stolons. This system of propagation, in addition to being slow, can spread plant diseases, particularly serious being viral. In vitro cult...

    Authors: Karla A. Quiroz, Miguel Berríos, Basilio Carrasco, Jorge B. Retamales, Peter D. S. Caligari and Rolando García-Gonzáles

    Citation: Biological Research 2017 50:20

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  18. Content type: Research article

    Bromodomain-containing protein 4 (BRD4) inhibition is a new therapeutic strategy for many malignancies. In this study, we aimed to explore the effect of BRD4 inhibition by JQ1 on in vitro cell growth, migratio...

    Authors: Limei Wang, Xiuyin Wu, Ruolin Wang, Chengzhe Yang, Zhi Li, Cunwei Wang, Fenghe Zhang and Pishan Yang

    Citation: Biological Research 2017 50:19

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  19. Content type: Review

    Realgar is a naturally occurring arsenic sulfide (or Xionghuang, in Chinese). It contains over 90% tetra-arsenic tetra-sulfide (As4S4). Currently, realgar has been confirmed the antitumor activities, both in vitr...

    Authors: Peng Chen, Ruixiang Xu, Lei Yan, Zhengrong Wu, Yan Wei, Wenbin Zhao, Xin Wang, Qinjian Xie and Hongyu Li

    Citation: Biological Research 2017 50:17

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  20. Content type: Research article

    Cocaine- and amphetamine-regulated transcript (CART), discovered initially by via differential display RT-PCR analysis of brains of rats administered cocaine, is expressed mainly in central nervous system or n...

    Authors: Pengfei Li, Xuejing Yu, Jianshan Xie, Xiaolei Yao, Wenzhong Liu, Jianbo Yao, Zhiwei Zhu and Lihua Lyu

    Citation: Biological Research 2017 50:18

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