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  1. Content type: Review

    Jojoba is considered a promising oil crop and is cultivated for diverse purposes in many countries. The jojoba seed produces unique high-quality oil with a wide range of applications such as medical and indust...

    Authors: Jameel R. Al-Obaidi, Mohammed Farouq Halabi, Nasser S. AlKhalifah, Shanavaskhan Asanar, Abdulrahman A. Al-Soqeer and M. F. Attia

    Citation: Biological Research 2017 50:25

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  2. Content type: Research article

    Airway remodeling is a key feature of asthma, characterized by increased proliferation of airway smooth muscle cells (ASMCs). S100A8 is a calcium-binding protein with a potential to regulate cell proliferation...

    Authors: Yu-Dong Xu, Yu Wang, Lei-Miao Yin, Ling-Ling Peng, Gyoung-Hee Park and Yong-Qing Yang

    Citation: Biological Research 2017 50:23

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  3. Content type: Research article

    Hypertrophic scarring (HS) is a severe disease, and results from unusual wound healing. Col1A1 could promote the hypertrophic scar formation, and the expression of Col1A1 in HS tissue was markedly higher than ...

    Authors: Sheng Bi, Linlin Chai, Xi Yuan, Chuan Cao and Shirong Li

    Citation: Biological Research 2017 50:22

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  4. Content type: Research article

    Multiple techniques exist for detecting Mycobacteria, each having its own advantages and drawbacks. Among them, automated culture-based systems like the BACTEC-MGIT™ are popular because they are inexpensive, reli...

    Authors: Roli Kargupta, Sachidevi Puttaswamy, Aiden J. Lee, Timothy E. Butler, Zhongyu Li, Sounak Chakraborty and Shramik Sengupta

    Citation: Biological Research 2017 50:21

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  5. Content type: Short report

    Vegetative propagation of Fragaria sp. is traditionally carried out using stolons. This system of propagation, in addition to being slow, can spread plant diseases, particularly serious being viral. In vitro cult...

    Authors: Karla A. Quiroz, Miguel Berríos, Basilio Carrasco, Jorge B. Retamales, Peter D. S. Caligari and Rolando García-Gonzáles

    Citation: Biological Research 2017 50:20

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  6. Content type: Research article

    Bromodomain-containing protein 4 (BRD4) inhibition is a new therapeutic strategy for many malignancies. In this study, we aimed to explore the effect of BRD4 inhibition by JQ1 on in vitro cell growth, migratio...

    Authors: Limei Wang, Xiuyin Wu, Ruolin Wang, Chengzhe Yang, Zhi Li, Cunwei Wang, Fenghe Zhang and Pishan Yang

    Citation: Biological Research 2017 50:19

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  7. Content type: Research article

    Cocaine- and amphetamine-regulated transcript (CART), discovered initially by via differential display RT-PCR analysis of brains of rats administered cocaine, is expressed mainly in central nervous system or n...

    Authors: Pengfei Li, Xuejing Yu, Jianshan Xie, Xiaolei Yao, Wenzhong Liu, Jianbo Yao, Zhiwei Zhu and Lihua Lyu

    Citation: Biological Research 2017 50:18

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  8. Content type: Review

    Realgar is a naturally occurring arsenic sulfide (or Xionghuang, in Chinese). It contains over 90% tetra-arsenic tetra-sulfide (As4S4). Currently, realgar has been confirmed the antitumor activities, both in vitr...

    Authors: Peng Chen, Ruixiang Xu, Lei Yan, Zhengrong Wu, Yan Wei, Wenbin Zhao, Xin Wang, Qinjian Xie and Hongyu Li

    Citation: Biological Research 2017 50:17

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  9. Content type: Research article

    Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechani...

    Authors: Zhihua Gan, Kun Han, Shuchen Lin, Haiyan Hu, Zan Shen and Daliu Min

    Citation: Biological Research 2017 50:15

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  10. Content type: Research article

    Kidney diseases are a global health problem. Currently, over 2 million people require dialysis or transplant which are associated with high morbidity and mortality; therefore, new researches focused on regener...

    Authors: Monica Maribel Mata-Miranda, Gustavo Jesus Vazquez-Zapien, Marlon Rojas-Lopez, Virginia Sanchez-Monroy, David Guillermo Perez-Ishiwara and Raul Jacobo Delgado-Macuil

    Citation: Biological Research 2017 50:14

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  11. Content type: Research article

    Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen. Apart from hectic fevers, dyspareun...

    Authors: Yun-Meng Da, Kai-Yu Niu, Shu-Ya Liu, Ke Wang, Wen-Juan Wang, Jing Jia, Li-Hua Qin and Wen-Pei Bai

    Citation: Biological Research 2017 50:11

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  12. Content type: Research article

    The muskrat is a seasonal breeder. Males secrete musk to attract females during the breeding season. The testosterone binding to the androgen receptor (AR) in musk glands of muskrat may play an important role ...

    Authors: Tianxiang Zhang, Dong Peng, Lei Qi, Weixuan Li, Mengyuan Fan, Jiachen Shen, Liangliang Yang, Yihua Wang, Wenxia Wang, Xiaolong Hu, Ruibo Cai, Ran Zhou, Yuting Wei, Juntong Zhou, Shuang Yang, Defu Hu…

    Citation: Biological Research 2017 50:10

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  13. Content type: Research article

    A number of dysregulated miRNAs have been identified and are proposed to have significant roles in the pathogenesis of type 2 diabetes mellitus or renal pathology. Alpinia oxyphylla has shown significant anti-inf...

    Authors: Guankui Du, Man Xiao, Xuezi Zhang, Maoyu Wen, Chi Pang, Shangfei Jiang, Shenggang Sang and Yiqiang Xie

    Citation: Biological Research 2017 50:9

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  14. Content type: Research article

    CD4+ T cells play an important role in the initiation of an immune response by providing help to other cells. Among the helper T subsets, interferon-γ (IFN-γ)-secreting T helper 1 (Th1) and IL-17-secreting T help...

    Authors: Youra Kang, Maheshwor Timilshina, Tae-gyu Nam, Byeong-Seon Jeong and Jae-Hoon Chang

    Citation: Biological Research 2017 50:8

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  15. Content type: Short report

    Earthworms are sensitive to toxic chemicals present in the soil and so are useful indicator organisms for soil health. Eisenia fetida are commonly used in ecotoxicological studies; therefore the assembly of a bas...

    Authors: Michelle Thunders, Jo Cavanagh and Yinsheng Li

    Citation: Biological Research 2017 50:7

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  16. Content type: Short report

    Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However, it is absent in typhoid sero...

    Authors: Rodrigo A. Espinoza, Cecilia A. Silva-Valenzuela, Fernando A. Amaya, Ítalo M. Urrutia, Inés Contreras and Carlos A. Santiviago

    Citation: Biological Research 2017 50:5

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  17. Content type: Research article

    Macrophages are a functionally heterogeneous cell population and depending on microenvironments they polarize in two main groups: M1 and M2. Glutamic acid and glutamate receptors may participate in the regulat...

    Authors: Lali Shanshiashvili, Elene Tsitsilashvili, Nino Dabrundashvili, Irine Kalandadze and David Mikeladze

    Citation: Biological Research 2017 50:4

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    The Erratum to this article has been published in Biological Research 2017 50:13

  18. Content type: Research article

    Cancer cells exhibit elevated levels of glucose uptake and may obtain pre-formed, diet-derived fatty acids from the bloodstream to boost their rapid growth; they may also use nucleic acid from their microenvir...

    Authors: Yanping Kong, Xianbo Zhang, Yongliang Zhao, Yanfang Xue and Ye Zhang

    Citation: Biological Research 2017 50:2

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  19. Content type: Short report

    Pathologic vascular smooth muscle cell (VSMC) proliferation and migration after vascular injury promotes the development of occlusive vascular disease. Therefore, an effective chemical agent to suppress aberra...

    Authors: Hyang-Hee Seo, Sang Woo Kim, Chang Youn Lee, Kyu Hee Lim, Jiyun Lee, Eunhyun Choi, Soyeon Lim, Seahyoung Lee and Ki-Chul Hwang

    Citation: Biological Research 2017 50:1

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  20. Content type: Research article

    Dendritic cells (DCs) are the most potent professional antigen-presenting cells for naive T cells to link innate and acquired immunity. Klotho, an anti-aging protein, participates in the regulation of Ca2+ depend...

    Authors: Nguyen Thi Xuan, Phi Thi Thu Trang, Nguyen Van Phong, Nguyen Linh Toan, Do Minh Trung, Nguyen Duy Bac, Viet Linh Nguyen, Nguyen Huy Hoang and Nong Van Hai

    Citation: Biological Research 2016 49:45

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  21. Content type: Research article

    The olfactomedin-like domain (OLFML) is present in at least four families of proteins, including OLFML2A and OLFML2B, which are expressed in adult rat retina cells. However, no expression of their orthologous ...

    Authors: Diana Cristina Pérez-Ibave, Rafael González-Alvarez, Margarita de La Luz Martinez-Fierro, Gabriel Ruiz-Ayma, Maricela Luna-Muñoz, Laura Elia Martínez-De-Villarreal, María De Lourdes Garza-Rodríguez, Diana Reséndez-Pérez, Jibran Mohamed-Noriega, Raquel Garza-Guajardo, Víctor Manuel Bautista-De-Lucío, Karim Mohamed-Noriega, Oralia Barboza-Quintana, Carlos Arámburo-De-La-Hoz, Hugo Alberto Barrera-Saldaña and Irám Pablo Rodríguez-Sánchez

    Citation: Biological Research 2016 49:44

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  22. Content type: Research article

    Computer-based technology is becoming increasingly essential in biological research where drug discovery programs start with the identification of suitable drug targets. 2-Methoxyestradiol (2ME2) is a 17β-estr...

    Authors: Michelle Helen Visagie, Seema Rummurat Jaiswal and Anna Margaretha Joubert

    Citation: Biological Research 2016 49:43

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  23. Content type: Research article

    Heavy metals can cause great harm to Siberian tigers in the natural environment. Cadmium (Cd2+) is an environmental contaminant that affects multiple cellular processes, including cell proliferation, differentiat...

    Authors: Hui Wang, Zheng Liu, Wenxiu Zhang, Ziao Yuan, Hongyi Yuan, Xueting Liu, Chunwen Yang and Weijun Guan

    Citation: Biological Research 2016 49:42

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  24. Content type: Research article

    Asthma is an increasing global health problem, and novel strategies to prevent or ameliorate the condition are needed. Here, the effects of 80 % ethanol extracts of Salvia plebeia R. Br. (SE) on an induced inflam...

    Authors: Hwan-Hee Jang, Su-Yeon Cho, Mi-Ju Kim, Jung-Bong Kim, Sung-Hyen Lee, Mee-Young Lee and Young-Min Lee

    Citation: Biological Research 2016 49:41

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  25. Content type: Research article

    New sequencing technologies have opened the way to the discovery and the characterization of pathogenic viruses in clinical samples. However, the use of these new methods can require an amplification of viral ...

    Authors: Nicolas Berthet, Stéphane Descorps-Declère, Andriniaina Andy Nkili-Meyong, Emmanuel Nakouné, Antoine Gessain, Jean-Claude Manuguerra and Mirdad Kazanji

    Citation: Biological Research 2016 49:39

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  26. Content type: Research article

    From ancient times, marine algae have emerged as alternative medicine and foods, contains the rich source of natural products like proteins, vitamins, and secondary metabolites, especially Chlorella vulgaris (C. ...

    Authors: Soundharrajan Ilavenil, Da Hye Kim, Mayakrishnan Vijayakumar, Srisesharam Srigopalram, Sang Gun Roh, Mariadhas Valan Arasu, Jong Suk Lee and Ki Choon Choi

    Citation: Biological Research 2016 49:38

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  27. Content type: Research article

    Several evidences indicate that hormones and neuropeptides function as immunomodulators. Among these, growth hormone (GH) is known to act on the thymic microenvironment, supporting its role in thymocyte differ...

    Authors: Marvin Paulo Lins, Larissa Fernanda de Araújo Vieira, Alfredo Aurélio Marinho Rosa and Salete Smaniotto

    Citation: Biological Research 2016 49:37

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  28. Content type: Research article

    Long non-coding RNAs can regulate tumorigenesis of various cancers. Dys-regulation of lncRNA-AFAP1-AS1 has not been studied in colorectal carcinoma (CRC). This study was to examine the function involvement of ...

    Authors: Xu Han, Lingling Wang, Yu Ning, Shuang Li and Zhenjun Wang

    Citation: Biological Research 2016 49:36

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  29. Content type: Erratum

    Authors: Carlos Fernández, Eloísa Ferreira, Eduardo San Miguel and Almudena Fernández-Briera

    Citation: Biological Research 2016 49:35

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    The Erratum to this article has been published in Biological Research 2016 49:35

    The original article was published in Biological Research 2016 49:35

  30. Content type: Research article

    Cellular senescence is induced either internally, for example by replication exhaustion and cell division, or externally, for example by irradiation. In both cases, cellular damages accumulate which, if not su...

    Authors: Shiva Marthandan, Uwe Menzel, Steffen Priebe, Marco Groth, Reinhard Guthke, Matthias Platzer, Peter Hemmerich, Christoph Kaether and Stephan Diekmann

    Citation: Biological Research 2016 49:34

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  31. Content type: Research article

    Glioblastoma is one of the most aggressive cancers of the brain. Malignant traits of glioblastoma cells include elevated migration, proliferation and survival capabilities. Galectins are unconventionally secre...

    Authors: Claudia Metz, Remziye Döger, Elizabeth Riquelme, Priscilla Cortés, Christopher Holmes, Ronan Shaughnessy, Claudia Oyanadel, Catalina Grabowski, Alfonso González and Andrea Soza

    Citation: Biological Research 2016 49:33

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  32. Content type: Research article

    Chitosan, the N-deacetylated derivative of chitin, is a cationic polyelectrolyte due to the presence of amino groups, one of the few occurring in nature. The use of chitosan in protein and drug delivery system...

    Authors: Xuebing Cao, Dongzhi Hou, Lei Wang, Sai Li, Shengang Sun, Qineng Ping and Yan Xu

    Citation: Biological Research 2016 49:32

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  33. Content type: Research article

    Physicochemical properties are frequently analyzed to characterize protein-sequences of known and unknown function. Especially the hydrophobicity of amino acids is often used for structural prediction or for t...

    Authors: Stefan Simm, Jens Einloft, Oliver Mirus and Enrico Schleiff

    Citation: Biological Research 2016 49:31

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  34. Content type: Research article

    α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. wh...

    Authors: Yu Liu, Lu Wang, Heng Liu, Rongrong Zhao, Bin Liu, Quanjuan Fu and Yuanhu Zhang

    Citation: Biological Research 2016 49:30

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  35. Content type: Research article

    Tear desiccation on a glass surface followed by transmitted-light microscopy has served as diagnostic test for dry eye. Four distinctive morphological domains (zones I, II, III and transition band) have been r...

    Authors: Felipe Traipe-Salas, Leonidas Traipe-Castro, Daniela Salinas-Toro, Daniela López, Felipe Valenzuela, Christian Cartes, Héctor Toledo-Araya, Claudio Pérez and Remigio López Solís

    Citation: Biological Research 2016 49:28

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  36. Content type: Research article

    Transient receptor potential melastatin 3 (TRPM3) cation channels are ubiquitously expressed by multiple cells and have an important regulatory role in calcium-dependent cell signalling to help maintain cellul...

    Authors: T. Nguyen, D. Staines, B. Nilius, P. Smith and S. Marshall-Gradisnik

    Citation: Biological Research 2016 49:27

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  37. Content type: Research article

    Zinc finger RNA binding protein (ZFR) is involved in the regulation of growth and cancer development. However, little is known about ZFR function in pancreatic cancer.

    Authors: Xiaolan Zhao, Man Chen and Jishan Tan

    Citation: Biological Research 2016 49:26

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    The Correction to this article has been published in Biological Research 2018 51:20

  38. Content type: Research article

    Acute respiratory distress syndrome (ARDS) is a potentially devastating form of acute inflammatory lung injury as well as a major cause of acute respiratory failure. Although researchers have made significant ...

    Authors: Min Wang, Jingjun Yan, Xingxing He, Qiang Zhong, Chengye Zhan and Shusheng Li

    Citation: Biological Research 2016 49:25

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  39. Content type: Research article

    This study was undertaken to determine the effects of varied salinity regimes on the morphological traits (plant height, number of leaves, number of flowers, fresh and dry weight) and major mineral composition...

    Authors: Md. Amirul Alam, Abdul Shukor Juraimi, M. Y. Rafii, Azizah Abdul Hamid, Farzad Aslani and M. A. Hakim

    Citation: Biological Research 2016 49:24

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  40. Content type: Research article

    Disturbance of the equilibrium between reactive oxygen species (ROS) and anti-oxidants (AOX) has been implicated in various diseases, including atherosclerosis, the most common pathologic process underlying co...

    Authors: Yosra Souiden, Hela Mallouli, Salah Meskhi, Yassine Chaabouni, Ahmed Rebai, Foued Chéour and Kacem Mahdouani

    Citation: Biological Research 2016 49:22

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  41. Content type: Research article

    Trichosanthin produced in the root tube of Trichosanthes kirilowii shows anti-tumor activity on a series of cancer cells including Hela, MCF-7, HL-60. But there is little information about its effect on the carci...

    Authors: JinLong Li, Hui Li, ZhaoLi Zhang, NianYue Wang and YongChen Zhang

    Citation: Biological Research 2016 49:21

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