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  1. Content type: Research article

    In the present study, we examined the inhibitory effects of a methanolic extract, dichloromethane fraction, water layer, and polyhydroxylated sterols (1–4) isolated from the Vietnamese starfish Protoreaster nodos...

    Authors: Nguyen Phuong Thao, Bui Thi Thuy Luyen, Jung Eun Koo, Sohyun Kim, Young Sang Koh, Nguyen Xuan Cuong, Nguyen Hoai Nam, Phan Van Kiem, Young Ho Kim and Chau Van Minh

    Citation: Biological Research 2015 48:12

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  2. Content type: Review

    The South American country Chile now boasts a life expectancy of over 80 years. As a consequence, Chile now faces the increasing social and economic burden of cancer and must implement political policy to deli...

    Authors: Jorge Jimenez de la Jara, Gabriel Bastias, Catterina Ferreccio, Cristian Moscoso, Sofia Sagues, Camilo Cid, Eduardo Bronstein, Cristian Herrera, Bruno Nervi, Alejandro Corvalan, Ethel V Velasquez, Pamela Gonzalez, Enrique Castellon, Eva Bustamante, Sergio Oñate, Eileen McNerney…

    Citation: Biological Research 2015 48:10

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  3. Content type: Research article

    Various health benefits have been attributed to Er-Miao-San (EMS), a traditional Chinese herbal formulation that contains equal amounts of cortex phellodendri (Phellodendron amurense Ruprecht) and rhizoma atracty...

    Authors: Seunghee Bae, Younjung Jung, Yeong Min Choi and Shunhua Li

    Citation: Biological Research 2015 48:8

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  4. Content type: Research article

    The present study was conducted in order to evaluate the fatty acid profile, anti-oxidant and anti-bacterial activities from the microwave aqueous extract of the leaves of three different varieties of Labisia pum...

    Authors: Ehsan Karimi, Hawa ZE Jaafar, Ali Ghasemzadeh and Mahdi Ebrahimi

    Citation: Biological Research 2015 48:9

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  5. Content type: Research article

    In this paper, we have studied the essential oils chemical composition of the leaves of seven Eucalyptus species developed in Tunisia. Eucalyptus leaves were picked from trees growing in different arboretums in T...

    Authors: Khaled Sebei, Fawzi Sakouhi, Wahid Herchi, Mohamed Larbi Khouja and Sadok Boukhchina

    Citation: Biological Research 2015 48:7

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  6. Content type: Research article

    Mesenchymal stem cells (MSCs) are considered the best candidate in stem cells therapy due to their multipotent differentiation ability, low expression of co-stimulatory molecules (CD80, CD86, CD34 and HLA-II) ...

    Authors: Li Zhang, Dan Liu, Dan Pu, Yanwen Wang, Li Li, Yanqi He, Yalun Li, Lei Li and Weimin Li

    Citation: Biological Research 2015 48:6

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  7. Content type: Research article

    The aim of our research work was to quantify total flavonoid contents in the leaves of 13 plant species family Asteraceae, 8 representatives of family Lamiaceae and 9 plant species belonging to family Rosaceae, u...

    Authors: Oksana Sytar, Klaudia Bruckova, Elena Hunkova, Marek Zivcak, Kiessoun Konate and Marian Brestic

    Citation: Biological Research 2015 48:5

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  8. Content type: Research article

    Honey is a natural product obtained from the nectar that is collected from flowers by bees. It has several properties, including those of being food and supplementary diet, and it can be used in cosmetic produ...

    Authors: Kanyaluck Jantakee and Yingmanee Tragoolpua

    Citation: Biological Research 2015 48:4

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  9. Content type: Research article

    Gap junctions between β-cells participate in the precise regulation of insulin secretion. Adherens junctions and their associated proteins are required for the formation, function and structural maintenance of...

    Authors: Ana Flávia Marçal-Pessoa, Carmen Lucia Bassi-Branco, Cristiana dos Santos Barbosa Salvatierra, Luiz Fabrizio Stoppiglia, Letícia Martins Ignacio-Souza, Sílvia Regina de Lima Reis, Roberto Vilela Veloso, Marise Auxiliadora de Barros Reis, Everardo Magalhães Carneiro, Antonio Carlos Boschero, Vanessa Cristina Arantes and Márcia Queiroz Latorraca

    Citation: Biological Research 2015 48:3

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  10. Content type: Research article

    The Eurasian grapevine (Vitis vinifera L.) is the most widely cultivated and economically important horticultural crop in the world. As a one of the origin area, Anatolia played an important role in the diversifi...

    Authors: Sadiye Peral Eyduran, Meleksen Akin, Sezai Ercisli, Ecevit Eyduran and David Maghradze

    Citation: Biological Research 2015 48:2

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  11. Content type: Research article

    Curcuma longa Linnaeus and Zingiber officinale Roscoe are two main representatives of Zingiberaceae family studied for a wide range of therapeutic properties, including: antioxidant, anti-infla...

    Authors: Corina Danciu, Lavinia Vlaia, Florinela Fetea, Monica Hancianu, Dorina E Coricovac, Sorina A Ciurlea, Codruţa M Şoica, Iosif Marincu, Vicentiu Vlaia, Cristina A Dehelean and Cristina Trandafirescu

    Citation: Biological Research 2015 48:1

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  12. Content type: Research article

    Based on the ethnomedicinal uses and the effective outcomes of natural products in various diseases, this study was designed to evaluate Isodon rugosus as possible remedy in oxidative stress, alzheimer’s and othe...

    Authors: Anwar Zeb, Abdul Sadiq, Farhat Ullah, Sajjad Ahmad and Muhammad Ayaz

    Citation: Biological Research 2014 47:76

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  13. Content type: Research article

    BrdU is a commonly used reagent in cell proliferation assays, and WST-1 measurement is widely used to detect cell viability. However, no previous study has formally reported the combination of the two assays, ...

    Authors: Lei-Miao Yin, Ying Wei, Wen-Qian Wang, Yu Wang, Yu-Dong Xu and Yong-Qing Yang

    Citation: Biological Research 2014 47:75

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  14. Content type: Research article

    Nitrosative and oxidative stress play a key role in obesity and diabetes-related mitochondrial dysfunction. The objective was to investigate the effect of curcumin treatment on state 3 and 4 oxygen consumption...

    Authors: María G Soto-Urquieta, Sergio López-Briones, Victoriano Pérez-Vázquez, Alfredo Saavedra-Molina, Gloria A González-Hernández and Joel Ramírez-Emiliano

    Citation: Biological Research 2014 47:74

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  15. Content type: Research article

    The hippocampal CA3 area contains large amounts of vesicular zinc in the mossy fiber terminals which is released during synaptic activity, depending on presynaptic calcium. Another characteristic of these syna...

    Authors: Carlos M Matias, Jose C Dionísio, Peter Saggau and Maria Emilia Quinta-Ferreira

    Citation: Biological Research 2014 47:73

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  16. Content type: Research article

    Rootstocks play an essential role to determining orchard performance of fruit trees. Pyrus communis and Cydonia oblonga are widely used rootstocks for European pear cultivars. The lack of rootstocks adapted to di...

    Authors: Ali Ikinci, Ibrahim Bolat, Sezai Ercisli and Ossama Kodad

    Citation: Biological Research 2014 47:71

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  17. Content type: Research article

    Vascular endothelial growth factor (VEGF) is involved in the growth of new blood vessels that feed tumors and kinesin spindle protein (KSP) plays a critical role in mitosis involving in cell proliferation. Sim...

    Authors: Chung Chinh Doan, Long Thanh Le, Son Nghia Hoang, Si Minh Do and Dong Van Le

    Citation: Biological Research 2014 47:70

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  18. Content type: Research article

    Ligularia fischeri (common name Gomchwi) is known for its pharmaceutical properties and used in the treatment of jaundice, scarlet-fever, rheumatoidal arthritis, and hepatic diseases; however, little is known abo...

    Authors: Hee-Sook Park, Hye-Young Choi and Gun-Hee Kim

    Citation: Biological Research 2014 47:69

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  19. Content type: Research article

    Tribolium castaneum (Herbst) is a major pest of stored grain-based products, and cause severe damage to cereal grains throughout the world. The present investigation was aimed to determine the pesticidal and pest...

    Authors: Alam Khan, Md Shariful Islam, Moizur Rahman, Tanjeena Zaman and Md Ekramul Haque

    Citation: Biological Research 2014 47:68

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  20. Content type: Research article

    Marine invertebrate-associated microbial communities are interesting examples of complex symbiotic systems and are a potential source of biotechnological products.

    Authors: Aileen O’Connor-Sánchez, Adán J Rivera-Domínguez, César De los Santos-Briones, Lluvia K López-Aguiar, Yuri J Peña-Ramírez and Alejandra Prieto-Davo

    Citation: Biological Research 2014 47:67

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  21. Content type: Research article

    The current era is facing challenges in the management of neoplasia and weeds control. The currently available anti-cancer and herbicidal drugs are associated with some serious side effects. Therefore numerous...

    Authors: Syed Muhammad Mukarram Shah, Abdul Sadiq, Syed Muhammad Hassan Shah and Shahzeb Khan

    Citation: Biological Research 2014 47:65

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  22. Content type: Research article

    Interactions between genes and their products give rise to complex circuits known as gene regulatory networks (GRN) that enable cells to process information and respond to external stimuli. Several important p...

    Authors: Gonzalo A Ruz, Tania Timmermann, Javiera Barrera and Eric Goles

    Citation: Biological Research 2014 47:64

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  23. Content type: Research article

    Cronobacter sakazakii is considered as an emerging foodborne pathogen. The aim of this study was to isolate and characterize virulent strains of Cronobacter sakazakii from food samples of Bangladesh.

    Authors: Md Fakruddin, Mizanur Rahaman, Monzur Morshed Ahmed and Md Mahfuzul Hoque

    Citation: Biological Research 2014 47:63

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  24. Content type: Research article

    The mortality of lung cancer (LC), increases each year in the world, in spite of any advances, in development of new drugs to advance stages of LC. The high incidence of LC has been associated with smoking hab...

    Authors: Marta I Adonis, Jose Díaz, Veronica R Miranda, Marco Chahuan, Alcides Zambrano, Hugo C Benitez, Monica Campos, Pablo Avaria, Ulises Urzúa, Pedro Marín, Mariela Gohurdett, Yasna Cisterna and Lionel Gil

    Citation: Biological Research 2014 47:62

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  25. Content type: Research article

    Telomeres are protective caps consisted of specific tandem repeats (5′-TTAGGG-3′). Shortening of telomeres at each cell division is known as “mitotic clock” of the cells, which renders telomeres as important r...

    Authors: Sevgi Ozden, Pinar Mega Tiber, Zerrin Ozgen, Hazan Ozyurt, Nedime Serakinci and Oya Orun

    Citation: Biological Research 2014 47:61

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  26. Content type: Research article

    During fish oocyte maturation, specific molecules are expressed and accumulated within oocyte until fertilization and embryo development. Special attention have been paid in members of the transforming growth ...

    Authors: Jaime Palomino, Giannina Herrera, Phillip Dettleff and Víctor Martínez

    Citation: Biological Research 2014 47:60

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  27. Content type: Research article

    Isodon rugosus is used traditionally in the management of hypertension, rheumatism, tooth-ache and pyrexia. Present study was arranged to investigate I. rugosus for phytoconstituents, phytotoxic and cytotoxic act...

    Authors: Anwar Zeb, Abdul Sadiq, Farhat Ullah, Sajjad Ahmad and Muhammad Ayaz

    Citation: Biological Research 2014 47:57

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  28. Content type: Research article

    The study was conducted to evaluate the in vitro thrombolytic activity, and in vivo analgesic, anti-inflammatory and antipyretic potentials of different hydrocarbon soluble extracts of Litsea glutinosa leaves for...

    Authors: Rumpa Bhowmick, Md Shahid Sarwar, Syed Masudur RahmanDewan, Abhijit Das, Binayok Das, Mir Muhammad NasirUddin, Md Siddiqul Islam and Mohammad Safiqul Islam

    Citation: Biological Research 2014 47:56

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  29. Content type: Research article

    The current study aims at evaluating the analgesic, anti-pyretic and anti-inflammatory properties of methanolic extract of the stem, bark and leaves of Launaea sarmentosa and Aegialitis rotundifolia roxb.

    Authors: Golam Sarwar Raju, Md Mizanur RahmanMoghal, Mohammad Salim Hossain, Md Mahadi Hassan, Md Mustahsan Billah, Sayed Koushik Ahamed and SM Masud Rana

    Citation: Biological Research 2014 47:55

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  30. Content type: Research article

    Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and c...

    Authors: Constant Anatole Pieme, Guru Kumar Santosh, Emmanuel Mouafo Tekwu, Tülin Askun, Hatice Aydeniz, Jeanne Yonkeu Ngogang, Shashi Bhushan and Ajit Kumar Saxena

    Citation: Biological Research 2014 47:54

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  31. Content type: Research article

    The occurrence and prevalence of integrons in clinical microorganisms and their role played in antimicrobial resistance have been well studied recently. As screening and detection of integrons are concerned, c...

    Authors: Guangchao Yu, Lei Chen, Chii-wann Lin, Bing Li, Hemiao Cui, Siyi Chen, Jian Miao, Huawei Bian, Dingqiang Chen and Yang Deng

    Citation: Biological Research 2014 47:53

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  32. Content type: Research article

    Testis-expressed sequence 101 (TEX101) was found to be highly expressed in testis and involved in acrosome reaction in previous studies. Recently, the metastasis suppressor function of TEX101 in cancer was dis...

    Authors: Cong-Cong Shen, Yu-Huan Kang, Lin Yu, Dan-Dan Cui, Yi He, Jin-Liang Yang and Lan-Tu Gou

    Citation: Biological Research 2014 47:52

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  33. Content type: Research article

    Tribolium castaneum (Herbst) is a harmful pest of stored grain and flour-based products in tropical and subtropical region. In the present study, rhizome of Drynaria quercifolia (J. Smith) was evaluated for pesti...

    Authors: Alam Khan, Md Hedayetul Islam, Md Ekramul Islam, Md Abdul Alim Al-Bari, Mst Shahnaj Parvin, Mohammed Abu Sayeed, Md Nurul Islam and Md Ekramul Haque

    Citation: Biological Research 2014 47:51

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  34. Content type: Research article

    Accumulating evidence indicates that reactive oxygen species (ROS) are an important etiological factor for the induction of dermal papilla cell senescence and hair loss, which is also known alopecia. Arctiin i...

    Authors: Seunghee Bae, Kyung Mi Lim, Hwa Jun Cha, In-Sook An, Jeong Pyo Lee, Kwang Sik Lee, Ghang Tai Lee, Kun Kook Lee, Ho Jung Jung, Kyu Joong Ahn and Sungkwan An

    Citation: Biological Research 2014 47:50

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  35. Content type: Research article

    The liver is an important organ for its ability to transform xenobiotics, making the liver tissue a prime target for toxic substances. The carotenoid bixin present in annatto is an antioxidant that can protect...

    Authors: Priscila R Moreira, Marcos A Maioli, Hyllana CD Medeiros, Marieli Guelfi, Flávia TV Pereira and Fábio E Mingatto

    Citation: Biological Research 2014 47:49

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  36. Content type: Research article

    Restricted space and close contact with conspecifics in captivity may be stressful for musk deer, as they are highly territorial and solitary in the wild. So we tested the effects of crowding on stress of fore...

    Authors: Lan He, Wen-Xia Wang, Lin-Hai Li, Bao-Qing Liu, Gang Liu, Shu-Qiang Liu, Lei Qi and De-Fu Hu

    Citation: Biological Research 2014 47:48

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  37. Content type: Research article

    Plant secondary metabolites are possess several biological activities such as anti-mutagenic, anti-carcinogenic, anti-aging, etc. Cell suspension culture is one of the most effective systems to produce seconda...

    Authors: Emine Sema Cetin, Zehra Babalik, Filiz Hallac-Turk and Nilgun Gokturk-Baydar

    Citation: Biological Research 2014 47:47

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  38. Content type: Research article

    Turkey is the main apricot producer in the world and apricots have been produced under both dry and irrigated conditions in the country. In this study, phenolic compounds and vitamins in fruits of one wild (Ze...

    Authors: Tuncay Kan, Muttalip Gundogdu, Sezai Ercisli, Ferhad Muradoglu, Ferit Celik, Mustafa Kenan Gecer, Ossama Kodad and Muhammad Zia-Ul-Haq

    Citation: Biological Research 2014 47:46

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  39. Content type: Research article

    The study was conducted to evaluate the in vitro antimicrobial activity, cytotoxic, and membrane stabilization activities, and in vivo antiemetic and antipyretic potentials of ethanolic extract, n-hexane and ethy...

    Authors: Mohammad Mobarak Hossain, Sayed Koushik Ahamed, Syed Masudur Rahman Dewan, Md Mahadi Hassan, Arif Istiaq, Mohammad Safiqul Islam and Mizanur Md Rahman Moghal

    Citation: Biological Research 2014 47:45

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  40. Content type: Research article

    Nitric oxide (NO) has been shown to be important in sperm function, and the concentration of NO appears to determine these effects. Studies have demonstrated both positive and negative effects of NO on sperm f...

    Authors: Jiangtao Wang, Qingliu He, Xingyu Yan, Youmei Cai and Junyi Chen

    Citation: Biological Research 2014 47:44

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  41. Content type: Research article

    Pure mucinous adenocarcinoma of the breast is a rare entity characterized by the production of variable amounts of mucin comprising 1% to 6% of breast carcinomas. Some mucinous adenocarcinomas have shown expre...

    Authors: Laura García-Labastida, Raquel Garza-Guajardo, Oralia Barboza-Quintana, Irám Pablo Rodríguez-Sanchez, Jesús Ancer-Rodríguez, Juan Pablo Flores-Gutierrez and Gabriela Sofía Gómez-Macías

    Citation: Biological Research 2014 47:43

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  42. Content type: Research article

    Tuberculosis (TB) is a respiratory tract disease caused by Mycobacterium tuberculosis infection. M. tuberculosis exploits immune privilege to grow and divide in pleural macrophages. Fibrates are associated with t...

    Authors: Sung-Jo Kim, Minho Hong, Ki Duk Song, Hak-Kyo Lee, Sungweon Ryoo and Tae-Hwe Heo

    Citation: Biological Research 2014 47:42

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  43. Content type: Research article

    The root of Angelica sinensis (AS), also known as “Dang-gui,” was a popular herbal medicine widely used in the treatment of gynecological diseases in China, Korea, and Japan for a long time. This study aimed to d...

    Authors: Won-Seok Lee, Jin-Han Lim, Myung-Soon Sung, Eun-Gyeong Lee, Yoo-Jeong Oh and Wan-Hee Yoo

    Citation: Biological Research 2014 47:41

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  44. Content type: Research article

    Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factor...

    Authors: Anabela Gonçalves Berenguer, Ana Teresa Fernandes, Susana Oliveira, Mariana Rodrigues, Pedro Ornelas, Diogo Romeira, Tânia Serrão, Alexandra Rosa and Rita Câmara

    Citation: Biological Research 2014 47:40

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  45. Content type: Research article

    Novel, in silico-designed anticancer compounds were synthesized in our laboratory namely, 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene ...

    Authors: Lisa Repsold, Thandi Mqoco, Elize Wolmarans, Sandra Nkandeu, Joji Theron, Tomek Piorkowski, Peet du Toit, Dirk van Papendorp and Annie Margaretha Joubert

    Citation: Biological Research 2014 47:39

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