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Fig. 4 | Biological Research

Fig. 4

From: Maintenance of chronicity signatures in fibroblasts isolated from recessive dystrophic epidermolysis bullosa chronic wound dressings under culture conditions

Fig. 4

Analysis of TGF-β signaling in RDEB-CW fibroblasts. (a-c) Western blot analysis of protein lysates derived from fibroblast cultures to detect the immature form of TGF-β1 and its receptor, TGFβRII (a), the SMAD2/SMAD3 proteins and their phosphorylated forms (p- SMAD2/p-SMAD3) (b), and the TGF-β1 activator molecule, TSP1 (c). (d) Densitometric analysis of all western blots displayed in (a-c). All data are expressed as mean ± SD. The experiments were performed with n = 3–4 per condition. Asterisks indicate significant differences by one-way ANOVA with Tukey post-hoc (p < 0.05)

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Biological Research

ISSN: 0717-6287

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