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Table 4 Lipid parameters, enzymatic antioxydant activity/polymorphism and CHD severity

From: MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity

Parameters 0-vessel (n = 13) 1-vessel (n = 42) 2-vessels (n = 35) 3-vessels (n = 16)
Total cholesterol (mmol/L) 4.11 ± 1.03 4.26 ± 1.07 4.59 ± 1.03 5.36 ± 1.41*
HDL-cholesterol (mmol/L) 0.86 ± 0.28 0.84 ± 0.26 0.81 ± 0.29 0.79 ± 0.23
LDL-cholesterol (mmol/L) 3.02 ± 0.93 3.15 ± 1.01 3.49 ± 1.04 4.19 ± 1.39*
Triglycerides (mmol/L) 1.14 ± 0.63 1.27 ± 0.65 1.34 ± 0.97 1.89 ± 1.00*
SOD activity, (U/gHb) 1246.9 ± 242.15 1112.4 ± 141.37 1065.6 ± 194.28 864.3 ± 229.08**, ‡
SOD genotypes, n (%), (CC/CT/TT) 4/6/3 10/21/11 7/18/10 3/7/6
(30.77/46.15/23.08) (23.81/50.0/26.19) (20.0/51.43/28.57) (18.75/43.75/37.5)
GPx activity, (U/gHb) 38.90 ± 7.89 44.09 ± 11.32 42.94 ± 11.15 43.65 ± 12.64
GPx genotypes, n (%), (CC/CT/TT) 7/8/1 22/17/3 21/12/2 9/6/1
(53.85/38.46/7.69) (52.38/40.47/7.14) (60.0/34.29/5.71) (56.26/37.5/6.25)
  1. * P < 0.05 compared with 0-vessel disease and P = 0.001 with 1-vessel disease
  2. ** P < 0.001 compared with 0-vessel disease and with 1-vessel disease and P = 0.002 with 2-vessels disease
  3.  P < 0.001 compared with 0-vessel disease, 1-vessel disease and 2-vessels disease