Fig. 2

YME1L overexpression prevents renal tubule injury in diabetic mice. A Representative images of H&E staining, MASSON staining, and SIRIUS RED staining and B, C the percentage of MASSON staining positive area and SIRIUS RED staining positive area were quantified (n = 4). Scale bar: 20 µm. D-H Western blotting and associated quantitative analysis of kidney α-SMA, FN, N-cadherin and vimentin expression in each group (n = 4). I Representative immunohistochemical staining showed the tubular expression of α-SMA, FN, and J, K the percentage of α-SMA, FN expression area was quantified (n = 4). Scale bar: 20 µm. Data are shown as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001