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Fig. 2 | Biological Research

Fig. 2

From: Integration of ATAC-seq and RNA-seq identifies MX1-mediated AP-1 transcriptional regulation as a therapeutic target for Down syndrome

Fig. 2

Transcription factor binding motifs enrichment in differential open chromatin regions. A The top 5 predicted binding motifs in the comparison between Normal and DS group. B Venn plot of the expression of enriched transcriptional factors in RNA-seq and ATAC-seq. C Heatmap of the expression of significantly upregulated 89 transcriptional factors in RNA-seq and ATAC-seq. D ATAC-seq tracks in the upstream promoter region of 7 key transcription factors in Normal and DS group

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