Fig. 5

Aβ plaque deposition counts in the DG area (A) Immunohistochemical representative plots of Aβ in the DG region of mice in each group. The magnification from left to right is 40x, 100x, 200x. B There were many Aβ plaques in the DG region of AD mice, and EA could reduce the deposition of Aβ plaques. But interference with Wnt5a expression did not affect the formation of Aβ plaques and did not inhibit the effect of EA. All data are presented as mean ± SD; n = 3 mice; ^***P < 0.001 vs. WT group; ^##P < 0.01 vs. 5 × FAD group