| SHR | SHR + MLN | SHR + ZOFE | SHR + MLN + ZOFE |
---|---|---|---|---|
n | 20 | 20 | 20 | 20 |
ΔSBP (%) | 5.87 ± 2.31 | 7.16 ± 2.83 | -2.69 ± 2.04 | 6.65 ± 2.45 |
ΔBW (%) | 6.05 ± 0.44 | 8.38 ± 0.45* | 3.08 ± 0.8** | 5 ± 0.71+++ |
HW (g) | 1.12 ± 0.04 | 1.21 ± 0.03 | 1.1 ± 0.01 | 1.04 ± 0.03+ |
HW/BW (mg/g) | 3.72 ± 0.14 | 3.78 ± 0.09 | 3.46 ± 0.03 | 3.4 ± 0.09+ |
VF (g) | 7.83 ± 0.33 | 8.99 ± 0.3* | 8.17 ± 0.39 | 8.07 ± 0.19 |
VF/BW (mg/g) | 25.1 ± 0.86 | 28.1 ± 0.93* | 25.59 ± 1.07 | 26.24 ± 0.5 |
H2S plasma (µM) | 11.89 ± 2.41 | 22.7 ± 8.48*** | 14.27 ± 3.65 | 20.23 ± 6.74** |
H2S heart (nM/mg) – basal | 826 ± 25.99 | 1020.67 ± 41.33*** | 1818.37 ± 127.84*** | 1079.76 ± 18.89***§§§ |
H2S heart (nM/mg) – activated | 1062.67 ± 61.76 | 1534 ± 91.17** | 2263.27 ± 223.52*** | 2020.24 ± 105.84***++ |