Fig. 3

GSEA plots showing most enriched biological pathway in in the IAs group compared with the STAs group. a The first significant enriched gene set is vascular smooth muscle contraction (ES = 0.483, NES = 1.654, P < 0.05). b The second significant enriched gene set is ECM receptor interaction (ES = − 0.483, NES = − 1.601, P < 0.05). c The third significant enriched gene set is p53 signaling pathway (ES = − 0.479, NES = − 1.689, P < 0.05). d The fourth significant enriched gene set is NOD like receptor signaling pathway (ES = − 0.598, NES = − 1.624, P < 0.05). e The fifth significant enriched gene set is apoptosis (ES = − 0.441, NES = − 1.5715, P < 0.05). f The sixth significant enriched gene set is Toll like receptor signaling pathway (ES = − 0.576, NES = − 1.709, P < 0.05)