Fig. 8Â From: S-Nitrosylation in endothelial cells contributes to tumor cell adhesion and extravasation during breast cancer metastasisSecreted factors from tumor cells can activate the S-nitrosylation pathway in the endothelium to promote VCAM-1 expression in the cell surface leading to binding of tumor cell or leukocyte to promote extravasation and posterior development of metastasisBack to article page