Fig. 5
From: Mucin1 induced trophoblast dysfunction in gestational diabetes mellitus via Wnt/β-catenin pathway
Assessment of glucose uptake- and apoptosis-related proteins in HTR-8/SVneo cells after high glucose treatment and MUC1 knockdown. A: Determination of cell viability in HTR-8/SVneo cells from the control, sh-MUC1, HG and HG + sh-MUC1 groups after 0, 24, 48 and 72 h of incubation by CCK-8 assay. B-F, B1-F1: Western blotting data showing the expression of MUC1 (B), GLUT4 (C), INSR (D), Bcl-2 (E) and Caspase3 (F) in HTR-8/SVneo cells. B1-F1 shows the quantitative analysis of the control, HG, sh-MUC1 and HG + sh-MUC1 groups. All statistical data are presented as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001. HG: high glucose