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Table 3 Clinical evaluation of patients and control (all from the same family)

From: Functional defects in hiPSCs-derived cardiomyocytes from patients with a PLEKHM2-mutation associated with dilated cardiomyopathy and left ventricular non-compaction

 

Patient age at onset and gender

Main clinical manifestations

Cells source

DCM-R (patient)

16, male

Severe LV dilatation. Severe global LV dysfunction. Ventricular tachycardia

Primary human fibroblasts from skin punch

DCM-O (patient)

13, male

Severe LV dilatation. Severe global LV dysfunction

Primary human fibroblasts from pacemaker replacement procedure

DCM-C (Control)

12, male

Control from the same family

Primary human fibroblasts from skin punch