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Fig. 4 | Biological Research

Fig. 4

From: Activation of a hypothalamus-habenula circuit by mechanical stimulation inhibits cocaine addiction-like behaviors

Fig. 4

In vivo extracellular single-unit recordings of LHb neurons during mechanical stimulation. A Experimental schedule. B Single-unit discharges from LHb neurons for total 30 min. C Individual percent change of spike frequency/sec before (Baseline) and after cocaine (Post-Cocaine) and the mean percent change (red filled circle). D Individual percent change of spike frequency/sec before (Post-Cocaine) and after MS (MS) and the mean percent change (red filled circle). Mean spike frequency/sec before and after cocaine and/or MS. Single-unit activities of LHb neurons were evoked during MS in cocaine-injected rats. *P < 0.001. MS, mechanical stimulation of ulnar nerve. n = 6

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