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Table 1 Physiological parameters in adult mice treated with 200 mg/kg UDCA

From: Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux

Physiological parameter

Control

UDCA

FFM (g)

14.98 ± 0.94

10.21 ± 0.75*

TBW (mL)

10.97 ± 0.67

7.47 ± 0.55*

FM (g)

4.16 ± 0.45

7.14 ± 0.80*

Muscle mass (mg)

EDL

10.08 ± 0.39

7.32 ± 0.21*

TA

42.76 ± 1.20

37.51 ± 1.05*

GAST

109.5 ± 2.5

100.6 ± 1.4*

SOL

9.66 ± 0.29

7.77 ± 0.20*

DIA

37.62 ± 2.13

31.91 ± 1.53*

Body weight (g)

Initial

30.13 ± 1.9

31.31 ± 3.1

Final

29.10 ± 1.5

30.53 ± 1.9

  1. Data correspond to mean ± SEM (n = 5–6 animals per condition). Data for Body weight correspond to mean ± SD (n = 6 animals per condition). *p < 0.05, t-test. DIA diaphragm, EDL extensor digitorum longus, FFM fat-free mass, FM fat mass, GAST gastrocnemius, SOL soleus, TA tibialis anterior, TBW total body water, UDCA ursodeoxycholic acid
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Biological Research

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