Table 2 Examples of the reciprocal effects observed following the variation of the cytosolic pool of glutathione and other thiols in the presence of oxyanions (selenite and/or tellurite) in different bacterial species

Selenite

 Rsp. rubrum

R. capsulatus

*Inhibition of glutathione biosynthesis in cells grown in the presence of selenite

Decrease of selenite reduction rate

[75]

 Stenotrophomonas maltophilia

*Inhibition of glutathione biosynthesis in cells grown in the presence of selenite

Inhibition of selenite reduction as a function of the inhibitor* amount

[152]

 Stenotrophomonas maltophilia

Expression of genes involved in glutathione biosynthesis

Induction of glutamate/cysteine ligase and glutathione synthetase

[152]

 Streptomyces sp. ES2-5

*Inhibition of glutathione biosynthesis in cells grown in the presence of selenite

Decrease of reduced thiols (RSH) following exposure to selenite

[153]

 Achrobactrum sp. MPV1

*Inhibition of glutathione biosynthesis in cells grown in the presence of selenite

Delay in selenite reduction to Se⁰

[87]

 Achrobactrum sp. MPV1

Determination of reduced thiols (RSH) in cells exposed to selenite

Decrease of reduced thiols (RSH) following the exposure to selenite

[87]

Tellurite

 E. coli

Determination of reduced thiols (RSH) in cells lysates with DTNB as a reagent

Decrease of RSH amount in cells grown in the presence of tellurite

[2]

 E. coli

HPLC-analysis of low MW compounds from cells grown in the presence of tellurite

Glutathione is the major target of tellurite toxicity

[135]

 Pseudomonas pseudoalcaligenes

Determination of reduced thiols (RSH) in cell lysates

Decrease of RSH amount in cells grown in the presence of tellurite

[103]

 Geobacter stearothermophilus

Expression of genes involved in cysteine metabolism (cysA, cysB, cysC, cysE, cysI, cysM,cysK) in the presence of tellurite

Induction of the expression of cys genes in parallel with decrease of various reduced thiols

[154]