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Fig. 5 | Biological Research

Fig. 5

From: Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Fig. 5

Downregulation of YAP1 and JAG1 was observed in MDA-MB-231 cells with linc-OIP5 knockdown. a Immunoblot confirmed linc-OIP5 siRNA remarkably decreased the protein expressions of YAP1 and JAG1. b qRT-PCR was used to check the mRNA levels of YAP1 and JAG1 after linc-OIP5 knockdown. c Linc-OIP5 siRNA decreased the JAG1 levels in the conditioned medium of MDA-MB-231 cells by ELISA analysis. NS no statistical difference, *P < 0.05, ** P < 0.01, *** P < 0.001

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