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Fig. 4 | Biological Research

Fig. 4

From: Edaravone alleviates cell apoptosis and mitochondrial injury in ischemia–reperfusion-induced kidney injury via the JAK/STAT pathway

Fig. 4

Edaravone inhibited IR-induced kidney apoptosis via JAK/STAT pathway. a Representative western blot bands showed that the expression of JAK2, p-JAK2, STAT1, p-STAT1, STAT3, p-STAT3, Bax and Bcl-2. b–d Bar graph showed the expression of p-JAK2/JAK2, p-STAT1/STAT1 and p-STAT3/STAT3 after normalized by the sham data. e Bar graph showed the expression of Bax, Bcl-2 protein and Bax/Bcl-2 after normalized by the sham data. Data are represented as mean ± SEM (n = 10 per group), *P < 0.05, **P < 0.01, ***P < 0.001 vs. sham; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. IR

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Biological Research

ISSN: 0717-6287

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