Fig. 5

CASC11 involved in the activating of Wnt/β-catenin signaling pathway. a TOP/FOP-Flash luciferase reporter assay was used to analyze the effect of CASC11 on the activity of Wnt/β-catenin signaling pathway in HeLa cells and CaSki cells. b Western blot analysis was used to evaluate the expressions of total and nuclear β-catenin in si-CASC-transfected HeLa cells and pcDNA 3.1-CASC11-transfected CaSki cells. Data were shown as the mean ± SD of 3 independent experiments. *p < 0.5; **p < 0.01; ***p < 0.001