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Fig. 4 | Biological Research

Fig. 4

From: ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

Fig. 4

ATPR induces differentiation in human NB4 and THP-1 cells. a NB4 cells were treated with ATPR (10−6 M) for different durations (0–72 h). CD11b and CD14 expression was analyzed by flow cytometry. b THP-1 cells were treated with ATPR (10−6 M) for different durations (0–72 h). CD11b and CD1 expression was analyzed by flow cytometry. c NB4 and THP-1 cells were treated with ATPR (10−6 M) for different durations (0–72 h). Then, the protein expression of CD11b was assessed by western blot. d NB4 and THP-1 cells were treated with ATPR (10−6 M) for 72 h, and the NBT reduction assay detected cell differentiation. *p < 0.05, **p < 0.01 versus control group

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