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Fig. 2 | Biological Research

Fig. 2

From: ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

Fig. 2

ATPR inhibits cell proliferation in human NB4 and THP-1 cells. a, b Dose- and time-dependent effects of ATPR on NB4 and THP-1 cells. NB4 and THP-1 cells were exposed to various concentrations (0, 10−9, 10−8, 10−7, 10−6, or 10−5 M) of ATPR for 24–72 h, followed by the determination of cell viability using the CCK8 assay. Values are presented as the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 versus control group

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