Fig. 1

The effect of Quinalizarin and CX-4945 on CK2 kinase activity and cell viability in human endothelial cells. a HUVECs were treated with DMSO, 25 μM Quinalizarin, or 10 μM CX-4945 for 1 h, 6 h, or 24 h. After cell lysis, in vitro kinase assay was conducted to measure CK2 kinase activity. Mean ± SD were calculated for three independent experiments (**p < 0.01, ***p < 0.001). b Protein expressions of CK2 α, α′ and β subunits in HUVECs were assessed by Western blot. c HUVECs were treated as described above. Cell viability was determined by CCK8 assay. Mean ± SD were calculated for three independent experiments (***p < 0.001)