Fig. 5
From: IRF2–INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells
Effect of IRF2–INPP4B on proliferation and apoptosis of AML cells. The cell proliferation (a) and apoptosis assays (b) in OCI/AML-2 and THP-1 cells transfected with vector, IRF2 and INPP4B after treatment with 3-MA. The cell proliferation (c) and apoptosis assays (d) in OCI/AML-2 and THP-1 cells transfected with vector, IRF2 and INPP4B after treatment with si-Ctrl, si-IRF2 and si-INPP4B. *P < 0.05 vs. the DMSO-treatment cells; #P < 0.05 vs. the si-Ctrl transfected cells