Fig. 2
From: IRF2–INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells
The effect of IRF2 or INPP4B overexpression on the autophagy of AML cells. a The mRNA and protein levels of IRF2 in OCI/AML-2 cells transfected with vector, IRF2, si-Ctrl and si-IRF2. b The mRNA and protein levels of INPP4B in OCI/AML-2 cells transfected with vector, INPP4B, si-Ctrl and si-INPP4B. The protein levels of Beclin-1, LC3-I, LC3-II (c) and P62 and the labeled number of GFP-LC3 vacuoles-positive cells (d) in OCI/AML-2 and THP-1 cells in the groups of blank, vector, IRF2 and INPP4B. *P < 0.05 vs. the vector-transfected cells; #P < 0.05 vs. the si-Ctrl transfected cells