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Table 4 The terms enriched for the genes in the significant module (only listed terms with p-value < 0.01)

From: Identification of the targets of hematoporphyrin derivative in lung adenocarcinoma using integrated network analysis

Category Term Count P-value Gene symbol
BP GO:0006413 ~ translational initiation 7 2.35E−10 RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28
BP GO:0006412 ~ translation 7 2.20E−08 RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28
BP GO:0000086 ~ G2/M transition of mitotic cell cycle 6 3.17E−08 HSP90AA1, TUBGCP5, CCP110, CEP78, AKAP9, CEP63
BP GO:0006415 ~ translational termination 5 3.21E−07 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0016259 ~ selenocysteine metabolic process 5 3.70E−07 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0006414 ~ translational elongation 5 5.47E−07 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0006614 ~ SRP-dependent cotranslational protein targeting to membrane 5 8.12E−07 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0019083 ~ viral transcription 5 9.41E−07 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0001887 ~ selenium compound metabolic process 5 1.01E−06 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0000184 ~ nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 5 1.20E−06 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0019058 ~ viral life cycle 5 3.22E−06 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0000278 ~ mitotic cell cycle 6 8.02E−06 HSP90AA1, TUBGCP5, CCP110, CEP78, AKAP9, CEP63
BP GO:0044267 ~ cellular protein metabolic process 7 1.67E−05 RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28
BP GO:0010467 ~ gene expression 7 2.65E−05 RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28
BP GO:0006996 ~ organelle organization 5 4.52E−05 HSP90AA1, CCP110, CEP78, AKAP9, CEP63
BP GO:0034641 ~ cellular nitrogen compound metabolic process 5 6.51E−05 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0016032 ~ viral process 5 4.78E−04 RPL13, RPL15, RPL3, RPS10, RPL28
BP GO:0044281 ~ small molecule metabolic process 6 5.11E−03 HSP90AA1, RPL13, RPL15, RPL3, RPS10, RPL28
CC GO:0005829 ~ cytosol 13 1.28E−09 HSP90AA1, TUBGCP5, CCP110, RPL13, CEP78, RPL15, EIF2S2, RPL3, EIF5B, RPS10, AKAP9, CEP63, RPL28
CC GO:0022625 ~ cytosolic large ribosomal subunit 4 7.57E−06 RPL13, RPL15, RPL3, RPL28
CC GO:0005813 ~ centrosome 5 1.28E−04 TUBGCP5, CCP110, CEP78, AKAP9, CEP63
CC GO:0016020 ~ membrane 5 3.24E−02 HSP90AA1, RPL13, RPL15, RPS10, RPL28
CC GO:0005840 ~ ribosome 2 3.80E−02 RPL15, RPS10
MF GO:0044822 ~ poly(A) RNA binding 8 1.70E−06 HSP90AA1, RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28
MF GO:0003735 ~ structural constituent of ribosome 5 7.88E−06 RPL13, RPL15, RPL3, RPS10, RPL28
MF GO:0003723 ~ RNA binding 5 1.47E−04 RPL13, RPL15, EIF2S2, RPL3, RPL28
MF GO:0005515 ~ protein binding 11 9.64E−03 HSP90AA1, CCP110, RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, AKAP9, CEP63, RPL28
KEGG hsa03010 ~ ribosome 5 4.57E−06 RPL13, RPL15, RPL3, RPS10, RPL28
  1. BP biological process, CC cellular component, MF molecular function, KEGG Kyoto Encyclopedia of Genes and Genomes
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