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Table 4 The terms enriched for the genes in the significant module (only listed terms with p-value < 0.01)

From: Identification of the targets of hematoporphyrin derivative in lung adenocarcinoma using integrated network analysis

Category

Term

Count

P-value

Gene symbol

BP

GO:0006413 ~ translational initiation

7

2.35E−10

RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28

BP

GO:0006412 ~ translation

7

2.20E−08

RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28

BP

GO:0000086 ~ G2/M transition of mitotic cell cycle

6

3.17E−08

HSP90AA1, TUBGCP5, CCP110, CEP78, AKAP9, CEP63

BP

GO:0006415 ~ translational termination

5

3.21E−07

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0016259 ~ selenocysteine metabolic process

5

3.70E−07

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0006414 ~ translational elongation

5

5.47E−07

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0006614 ~ SRP-dependent cotranslational protein targeting to membrane

5

8.12E−07

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0019083 ~ viral transcription

5

9.41E−07

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0001887 ~ selenium compound metabolic process

5

1.01E−06

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0000184 ~ nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

5

1.20E−06

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0019058 ~ viral life cycle

5

3.22E−06

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0000278 ~ mitotic cell cycle

6

8.02E−06

HSP90AA1, TUBGCP5, CCP110, CEP78, AKAP9, CEP63

BP

GO:0044267 ~ cellular protein metabolic process

7

1.67E−05

RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28

BP

GO:0010467 ~ gene expression

7

2.65E−05

RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28

BP

GO:0006996 ~ organelle organization

5

4.52E−05

HSP90AA1, CCP110, CEP78, AKAP9, CEP63

BP

GO:0034641 ~ cellular nitrogen compound metabolic process

5

6.51E−05

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0016032 ~ viral process

5

4.78E−04

RPL13, RPL15, RPL3, RPS10, RPL28

BP

GO:0044281 ~ small molecule metabolic process

6

5.11E−03

HSP90AA1, RPL13, RPL15, RPL3, RPS10, RPL28

CC

GO:0005829 ~ cytosol

13

1.28E−09

HSP90AA1, TUBGCP5, CCP110, RPL13, CEP78, RPL15, EIF2S2, RPL3, EIF5B, RPS10, AKAP9, CEP63, RPL28

CC

GO:0022625 ~ cytosolic large ribosomal subunit

4

7.57E−06

RPL13, RPL15, RPL3, RPL28

CC

GO:0005813 ~ centrosome

5

1.28E−04

TUBGCP5, CCP110, CEP78, AKAP9, CEP63

CC

GO:0016020 ~ membrane

5

3.24E−02

HSP90AA1, RPL13, RPL15, RPS10, RPL28

CC

GO:0005840 ~ ribosome

2

3.80E−02

RPL15, RPS10

MF

GO:0044822 ~ poly(A) RNA binding

8

1.70E−06

HSP90AA1, RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, RPL28

MF

GO:0003735 ~ structural constituent of ribosome

5

7.88E−06

RPL13, RPL15, RPL3, RPS10, RPL28

MF

GO:0003723 ~ RNA binding

5

1.47E−04

RPL13, RPL15, EIF2S2, RPL3, RPL28

MF

GO:0005515 ~ protein binding

11

9.64E−03

HSP90AA1, CCP110, RPL13, RPL15, EIF2S2, RPL3, EIF5B, RPS10, AKAP9, CEP63, RPL28

KEGG

hsa03010 ~ ribosome

5

4.57E−06

RPL13, RPL15, RPL3, RPS10, RPL28

  1. BP biological process, CC cellular component, MF molecular function, KEGG Kyoto Encyclopedia of Genes and Genomes