Fig. 4
From: The deubiquitinase USP38 affects cellular functions through interacting with LSD1
USP38 promotes the proliferation of HCT116 cells. a After the vector or Flag-tagged USP38 gene was transfected into LSD1 wild-type (WT, +/+) or single-allele knockout (KO, +/−) HCT116 cells, cell proliferation assays were performed with CCK-8 kits. An asterisk (*) indicates p < 0.05, compared to vector-transfected HCT116 wild-type cells. b After the vector or Flag-tagged USP38 gene was transfected into LSD1 wild-type (WT, +/+) HCT116 cells, western blotting was performed to detect the expression of cell cycle and apoptosis related proteins. An asterisk (*) indicates p < 0.05, compared to vector-transfected cells. Three independent experiments were performed