Fig. 1

a The FSC scatter data provide information on the relative size of the cells, whereas the SSC data estimate the granularity. Dot plot where each dot represents one event. Here only 10,000 events are shown to avoid oversaturation of dots. Monocyte population defined by FSC and SSC properties are shown on the graph. b Peripheral blood cells were stained with anti-CD11b-APC antibody or isotype control to confirm the monocyte population. The flow cytometric immunophenotipic data revealed that the subset of monocytes defined by FSC and SSC expressed CD11b antigen (~ 40% positive cells). c Monocytes as percentage of whole lysed (depleted erythrocytes) peripheral blood cells. Bars graph represents the proportion of total circulating monocytes in apoE^−/− and age-matched WT mice. d Lipid profile in apoE^−/− and WT mice. Values are means ± SEM, *p < 0.05 vs. the respective young group, ^#p < 0.05 vs. age-matched WT group