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Fig. 5 | Biological Research

Fig. 5

From: miR-214 ameliorates acute kidney injury via targeting DKK3 and activating of Wnt/β-catenin signaling pathway

Fig. 5

miR-214 protected against AKI in vivo through targeting Dkk3 and activating Wnt/β-catenin pathway. miR-214 or miR-con was intraperitoneally injected into mice, followed by ischemic surgery. a qRT-PCR analysis of miR-214 expression in I/R-induced rat AKI model and sham mice. The serum levels of BUN (b), SCr (c), and Urine Kim-1 (d) level in I/R-induced rat AKI model and sham mice. e Western blot analysis of Bcl-2, Bax and fibronectin in I/R-induced rat AKI model and sham group. f The protein levels of DKK3, β-catenin, c-myc, and cyclin D1 in I/R-induced rat AKI model and sham group. Each experiment was independently repeated 3 times. *P < 0.05

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Biological Research

ISSN: 0717-6287

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