Fig. 5

Serous acinar cells of four groups. a SHAM group; b OVX group; c OVX + E2 group; d OVX + iCR group. The rough endoplasmic reticulum was arranged like the fingerprint, with the nucleus, mitochondria and black secretory granules embedded in it in a. In picture b, the rough endoplasmic reticulum arrangement was sparser; the mitochondrial lesions were conspicuous with broken ridges, and the secretory granules had declined in number and volumes. In picture c, the rough endoplasmic reticulum was arranged orderly and the mitochondria were healthy. But the number of secretory granules was decreased. In d, the rough endoplasmic reticulum seemed normal, but mitochondrial lesions could still be found. The number of secretory granules was declined with less dense coloration. Asterisk indicates the secretory granules. White arrows indicate the mitochondria. White arrow heads indicate the rough endoplasmic reticulum. Bars 1 μm