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Table 4 The allele-specific copy number (ASCN) of the 11 genes with high loss of heterozygosity (LOH) frequency

From: Analysis of gene expression changes associated with human carcinoma-associated fibroblasts in non-small cell lung carcinoma

Gene symbol

The copy number of A allele

The copy number of B allele

Proportion (%)

Description

Log2 FC

LXN

2

0

100

Loss of the one allele,gain of another allele

−1.9225

RASL11A

2

0

100

Loss of the one allele,gain of another allele

−0.885

KCNRG

0

2

100

Loss of the one allele,gain of another allele

−0.6275

TFAP2C

0.3

1.7

70

Copy neutral LOH in 70%

0.9875

SPHK1

0.3

1.7

70

Copy neutral LOH in 70%

0.6825

TP53INP1

1.6

0.4

60

Copy neutral LOH in 60%

−0.795

HOXD12

1.5

0.5

50

Copy neutral LOH in 50%

0.87

ERRFI1

1.5

0.5

50

Copy neutral LOH in 50%

−1.195

RPS6KA6

0.6

1.6

50

Loss of one allele in 50%

−1.12

DNAJB4

0.4

1.4

50

Copy neutral LOH in 50%

−1.02

ITGA7

0.5

1.5

50

Copy neutral LOH in 50%

−0.925

  1. Gene symbol the name of one gene, proportion the percentage of copy number of A allele minus copy number of B allele, Description the frequency of LOH, FC fold change