Fig. 3
From: Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease
CIH increased basal carotid chemosensory discharges and induced a potentiation of chemosensory responses to acute hypoxia. The chemosensory responses to various levels of inspired O2 (PO2 ≈ 100−1 %) were measured from one carotid sinus nerve of a sham rat (a) and from a rat exposed to cyclic hypoxic episodes (PO2 to 35 mmHg, 12 times per h during 8 h) for 21 days. (b) ƒcsn, frequency of carotid chemosensory discharges expressed in Hz. Rats were anesthetized with sodium pentobarbitone (40 mg/kg ip) and breathed spontaneously room air. Reprinted from Iturriaga et al. [8] with permission of John Wiley and Sons