Table 2 Cell cycle phase distribution of A549, HepG2 and HL-60 cells with various doses of karanjin for 72 h
From: Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells
Cell line | Group | Cell cycle distribution (%) | ||
|---|---|---|---|---|
G0/G1 | S | G2/M | ||
A549 | Control | 50.3 ± 2.0 | 40.5 ± 3.3 | 9.2 ± 1.5 |
4.0 µM | 51.6 ± 2.5 | 36.9 ± 3.0 | 11.2 ± 0.9 | |
6.0 µM | 39.0 ± 1.4** | 29.2 ± 1.7** | 31.8 ± 2.8** | |
8.0 µM | 14.0 ± 1.5** | 25.6 ± 2.6** | 60.4 ± 1.2** | |
HepG2 | Control | 49.9 ± 2.1 | 34.3 ± 2.1 | 15.8 ± 0.1 |
1.25 µM | 46.8 ± 1.8 | 34.7 ± 2.0 | 18.5 ± 2.6 | |
2.5 µM | 35.0 ± 2.2** | 43.3 ± 1.8** | 21.7 ± 1.0** | |
5.0 µM | 32.3 ± 1.8** | 42.8 ± 1** | 25 ± 1.0** | |
HL-60 | Control | 28.8 ± 3.6 | 63.1 ± 4.5 | 8.0 ± 0.8 |
2.0 µM | 9.6 ± 0.8** | 65.5 ± 2.6 | 24.9 ± 2.7** | |
4.0 µM | 4.2 ± 0.5** | 57.0 ± 0.9 | 38.8 ± 0.5** | |
6.0 µM | 4.9 ± 0.4** | 53.0 ± 1.7* | 42.1 ± 1.4** | |