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Table 2 Cell cycle phase distribution of A549, HepG2 and HL-60 cells with various doses of karanjin for 72 h

From: Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells

Cell line Group Cell cycle distribution (%)
G0/G1 S G2/M
A549 Control 50.3 ± 2.0 40.5 ± 3.3 9.2 ± 1.5
4.0 µM 51.6 ± 2.5 36.9 ± 3.0 11.2 ± 0.9
6.0 µM 39.0 ± 1.4** 29.2 ± 1.7** 31.8 ± 2.8**
8.0 µM 14.0 ± 1.5** 25.6 ± 2.6** 60.4 ± 1.2**
HepG2 Control 49.9 ± 2.1 34.3 ± 2.1 15.8 ± 0.1
1.25 µM 46.8 ± 1.8 34.7 ± 2.0 18.5 ± 2.6
2.5 µM 35.0 ± 2.2** 43.3 ± 1.8** 21.7 ± 1.0**
5.0 µM 32.3 ± 1.8** 42.8 ± 1** 25 ± 1.0**
HL-60 Control 28.8 ± 3.6 63.1 ± 4.5 8.0 ± 0.8
2.0 µM 9.6 ± 0.8** 65.5 ± 2.6 24.9 ± 2.7**
4.0 µM 4.2 ± 0.5** 57.0 ± 0.9 38.8 ± 0.5**
6.0 µM 4.9 ± 0.4** 53.0 ± 1.7* 42.1 ± 1.4**
  1. Results are expressed as mean ± SD values from three independent experiments.
  2. P value of less than 0.05 (* P < 0.05, ** P < 0.01, compared with the control group) are considered statistically significant.
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