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Table 3 Effect of methanolic extract of Rumex vesicarius L on SOD, CAT, MDA compared to silymarin in liver damaged rats

From: Cytotoxicity and hepatoprotective attributes of methanolic extract of Rumex vesicarius L.

Groups

Dosing

SOD (U/mg Hb)

CAT (U/mg Hb)

MDA (nmol/mg)

Group I

1%Tween 80

   

Control

5 ml/kg bw.p.o

3.48 ± 0.16

2.78 ± 0.09

12.4 ± 0.48

Group II

CCl4

2.23 ± 0.15

2.27 ± 0.10

24.2 ± 0.76

Toxic

1.5 ml/kg bw.i.p

   

Group III

Silymarin

4.52 ± 0.24

3.27 ± 0.11

15.3 ± 0.67

Positive control

50 mg/kgbw.p.o

   

Group IV

100 mg/kg bw.p.o

3.63 ± 0.15

2.87 ± 0.03

17.1 ± 0.53

Low dose

    

Group V

200 mg/kgbw.p.o

4.18 ± 0.24

3.35 ± 0.14

14.6 ± 0.54

High dose

    
  1. Each value represents the mean of 6 rats ± S.E. significant at P < 0.0001; as compared with the corresponding control group.
  2. SOD: superoxide dismutase; CAT: catalase; MDA = malondialdehyde.