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Table 2 Effect of methanolic extract of Rumex vesicarius L on plasma enzymes (SGOT, SGPT, ALP), Cholesterol, total bilirubin (T.B) and total protein (T.P) compared to silymarin in liver damaged rats

From: Cytotoxicity and hepatoprotective attributes of methanolic extract of Rumex vesicarius L.

Groups

Dosing

SGOT (U/L)

SGPT (U/L)

ALP (U/L)

T.P (mg/dL)

T.B (mg/dL)

Group I

1%Tween 80 5 ml/kg bw.p.o

119.26 ± 4.650

43.15 ± 3.832

440.7 ± 7.07

6.39 ± 0.35

0.70 ± 0.05

Group II

CCl4 1.5 ml/kg bw.i.p

275.0 ± 2.987

66.09 ± 2.469

492.5 ± 4.891

4.93 ± 0.13

1.41 ± 0.08

Group III

Silymarin 50 mg/kgbw.p.o

132.0 ± 0.653

45.96 ± 2.029

275.3 ± 3.150

5.52 ± 0.36

0.86 ± 0.04

Group IV

100 mg/kg bw.p.o

210.5 ± 0.697

62.52 ± 2.063

214.3 ± 2.843

5.03 ± 0.28

0.91 ± 0.03

Group V

200 mg/kgbw.p.o

177.3 ± 2.970

53.03 ± 2.95

308.7 ± 2.465

5.79 ± 0.23

0.98 ± 0.04

  1. Each value represents the mean of 6 rats ± S.E. significant at P > 0.0001; as compared with the corresponding control group.
  2. SGOT- serum glutamic oxaloacetic transaminase, SGPT -serum glutamic pyruvic transaminase, ALP- Alkaline phosphatase,
  3. TP- Total protein TB -Total bilirubin.