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Table 1 Anti-inflammatory effects of the extract/fractions on LPS-stimulated BMDCs

From: Anti-inflammatory components of the Vietnamese starfish Protoreaster nodosus

Extract/fractions IC 50 values (μg /mL) a
  IL -12 p40 IL- 6 TNF- α
CH2Cl2 fraction 0.60 ± 0.01 3.29 ± 0.09 10.29 ± 0.34
Water layer 4.03 ± 0.10 80.76 ± 1.96 >100
MeOH extract 2.48 ± 0.08 8.57 ± 0.21 26.19 ± 0.64
SB203580 b 2.52 ± 0.12 1.67 ± 0.13 3.65 ± 0.12
  1. aThe inhibitory effects are represented as giving 50% inhibition (IC50) relative to the vehicle control. These data represent the average values of three repeated experiments (mean ± SD). IC50 values for selected extracts are given in column IL-12 p40, IL-6 and TNF-α. Values <100 μg/mL are considered to be active.
  2. bSB203580 was used as a positive control.