Effects of different treatments on the induction of apoptosis in Hep3B cells. (A) Cell apoptosis was detected by Annexin V-FITC/PI double staining and FCM analysis. Cells in the lower left (LL) quadrant represented survivals; lower right (LR) quadrant represented early apoptosis; the upper right (UR) quadrant represented necrosis or post-apoptotic and the upper left (UL) quadrant represented detection of error allowed. (B) Values (intensity of fluorescent positive cells during early apoptotic events) were given as mean value ± standard deviation (SD) of triplicate. **p < 0.01 compared to untreated cell group, #p < 0.05 compared to siRNA cocktail treated cell group.