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Table 1 Concentration dependent cytotoxic potential of crude methanolic extracts of T. stocksianum and its sub-fractions against Brine shrimps nauplii

From: Extraction of saponins and toxicological profile of Teucrium stocksianum boiss extracts collected from District Swat, Pakistan

Samples/Drug

Conc 10 μg/ml

Conc 100 μ/ml

Conc 1000 μ/ml

LC50μ/ml

Crude saponins

55.555 ± 1.112%

63.332 ± 3.337%

94.444 ± 2.943

< 10

Methanolic extract

18.888 ± 5.886%

35.555 ± 2.943%

58.887 ± 2.944%

620

n- hexane fraction

37.777 ± 2.943%

42.221 ± 2.943%

67.777 ± 2.224%

80

Chloroform fraction

42.221 ± 2.943%

59.999 ± 1.926%

71.110 ± 2.943%

55

Ethyl acetate fraction

16.666 ± 1.926%

28.888 ± 1.112%

54.444 ± 2.943%

860

Aqueous fraction

12.221 ± 2.943%

27.777 ± 2.943%

49.998 ± 1.926%

1000

  1. Conc; concentration. Values are expressed as the mean ± SEM of three independent observations. Standard drug; Etoposide LD50 = 9.8 μg/ml.