Figure 1

IL-1β increased the proliferation of RASFs dose-dependently and EAAS inhibits IL-1β-induced proliferation of RASFs. IL-1β accelerated the proliferation of RASFs dose- and time-dependently (from 0.1 to 10 ng/mL). Results are presented as mean ± SD, n = 3. *p < 0.05 or †p < 0.01 versus day 0 (a). EAAS (100 μg/mL) significantly inhibited IL-1-induced proliferation of RASFs after 2, 3 days culture (p < 0.05) *p < 0.05 versus no IL-1β and EAAS, †p < 0.05 versus no IL-1β and EAAS, ‡p < 0.05 versus IL-1β without EAAS (b). EAAS inhibited IL-1β-induced proliferation of RASFs dose-dependently. *p < 0.05 versus no IL-1β, †p < 0.05, ‡p < 0.01 versus IL-1β without EAAS (c).