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Table 5 Skin prick tests positivity across SNP genotypes

From: Genetic polymorphisms and asthma: findings from a case–control study in the Madeira island population

Allergen panel    SNP genotypes   
    ADAM33-V4 C/G   
   n GG CG CC p-value OR (95% CI)
Dermatophagoides pteronyssinus (-) 23 0.043 0.348 0.609   
(+) 74 0 0.203 0.797   
  < 10 mm 44 0 0.295 0.705   
  ≥ 10 mm 30 0 0.067 0.933 0.016 1.325 (1.070-1.641)
Blomia tropicalis (-) 43 0.023 0.279 0.698   
  (+) 54 0 0.204 0.796   
  < 10 mm 42 0 0.262 0.738   
  ≥ 10 mm 12 0 0 1.00 0.047 1.355 (1.131-1.622)
    STAT6-21 C/T   
    CC CT TT   
Storage mites (-) 53 0.396 0.472 0.132   
  (+) 44 0.500 0.364 0.236   
  < 10 mm 35 0.514 0.429 0.057   
  ≥ 10 mm 9 0.444 0.111 0.444 0.003* 7.778 (1.682-35.962)
  1. Only significant associations are reported, in bold.
  2. Storage mites: Lepidoglyphus destructor, Glycifagus domesticus, Acarus siro, Euroglyphus maynei and Tyrophagus putrescentiae allergens, classified as ≥ 10 mm if at least one test resulted in wheal diameter ≥ 10 mm.*Recessive model.
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