Table 1 Topical anti-inflammatory effect of the total extract and primary fractions obtained from Cryptostegia grandiflora leaves
From: In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves
Treatment | Dose (mg/ear) | Ear weight differences (mg) | Inhibition percentage (%) |
|---|---|---|---|
Control (TPA + acetone) | — — — | 13.5 ± 0.6 | — — — |
Indomethacin | 0.5 | 7.4 ± 0.8 | 52.4 ± 6.2*** |
Cryptostegia grandiflora | |||
Total extract | 1.0 | 7.6 ± 0.1 | 42.1 ± 0.9*** |
Ether fraction | 1.0 | 8.1 ± 0.8 | 41.8 ± 8.0*** |
Dichloromethane fraction | 1.0 | 6.1 ± 0.5 | 52.9 ± 4.3*** |
Methanol fraction | 1.0 | 12.2 ± 0.4 | 6.8 ± 3.2 |