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Table 1 Topical anti-inflammatory effect of the total extract and primary fractions obtained from Cryptostegia grandiflora leaves

From: In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves

Treatment Dose (mg/ear) Ear weight differences (mg) Inhibition percentage (%)
Control (TPA + acetone) — — — 13.5 ± 0.6 — — —
Indomethacin 0.5 7.4 ± 0.8 52.4 ± 6.2***
Cryptostegia grandiflora
Total extract 1.0 7.6 ± 0.1 42.1 ± 0.9***
Ether fraction 1.0 8.1 ± 0.8 41.8 ± 8.0***
Dichloromethane fraction 1.0 6.1 ± 0.5 52.9 ± 4.3***
Methanol fraction 1.0 12.2 ± 0.4 6.8 ± 3.2
  1. Results are expressed as mean ± S.M.E. (n = 6) (***p <0.001 ANOVA, statistically significant compared with control group).