Inhibitory effect on NO• and PGE2 production by ether (A and C) and dichloromethane (B and D) fractions from Cryptostegia grandiflora on RAW 264.7 cells stimulated with LPS (10 μg/mL) for 24 h. 1400 W (10 μM) and Rofecoxib (10 μM) were employed as positive controls. Nitrite concentration in the culture medium was measured with the Griess reagent. PGE2 production was determined using a competitive ELISA kit (R&D Systems, USA). Experiments were carried out in triplicate and results show the mean ± S.E.M. (n = 12). **p < 0.01, ***p < 0.001, compared with LPS treated group.