Intraindividual similarities and interindividual differences in the morphological appearances of tear microdesiccates from single healthy subjects. Microdesiccates from 1-uL aliquots of two successive samples of tear fluid taken from single healthy subjects (same eye) displayed marked morphological similarities (neighbour images). Microdesiccates corresponding to four subjects (A, B, C and D) are shown. Note also some clear differences among microdesiccates from different subjects, although a general design is maintained. Microdesiccates in the figure were rated I-II (normal) in the conventional Rolando’s classification system.