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Fig. 1 | Biological Research

Fig. 1

From: Galectins in epithelial-mesenchymal transition: roles and mechanisms contributing to tissue repair, fibrosis and cancer metastasis

Fig. 1

Structure of galectins involved in EMT. Gal-1, Gal-2, and Gal-7 are prototypic galectins that contain a single CRD and a short N-terminal sequence that enables dimerization. Gal-4 and Gal-8 are tandem repeat galectins bearing N- and C-terminal CRDs separated by a linker peptide. These galectins also form dimers. Gal-3 belongs to the chimeric galectin type and contains a single CRD and a large amino-terminal non-lectin domain that contributes to self-aggregation

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