Fig. 2

Transcript abundance of target genes in embryos after IVC, with or without miR-148b. Embryos cultured from presumptive zygotes to blastocyst in SOF + 0.3% BSA (Control), supplemented with 1 µM control mimics (CMimic), or supplemented with 1 µM of miR-148b mimics (miR148b). Transforming growth factor-beta 2 receptor (TGFBR2); SMAD family member 1 (SMAD1); SMAD family member 2 (SMAD2); SMAD family member 3 (SMAD3); SMAD family member 5 (SMAD5); Bone morphogenetic protein receptor 2 (BMPR2); Ribosomal Protein S6 Kinase Beta-1 (RPS6KB1); POU Class 5 Homeobox 1 (POU5F1); Nanog Homeobox (NANOG). Data are the mean ± s.e.m. Different letters indicate significant difference (P ≤ 0.05) between treatments