Fig. 6

Effect of eMSC on endometrial fibrosis. (A) Representative Masson Trichrome stain images showing the degree of endometrial fibrosis in the mouse endometrium. Scale bar: 50 μm. (B) Relative square of fibrosis in the PBS group (blue bars) and the eMSC group (yellow bars) on Day 3, 7 and 14 post-surgery (n = 4). The injured uterine horn (L) was normalized against the control uterine horn (R) from the same animal. Relative gene expression of (C)Fn1, (D)Col1A1 and (E)Acta2 in the PBS group (blue bars) and the eMSC group (yellow bars) at different post-operative timepoints (n = 4). Results are presented as mean ± SD; *P < 0.05. Abbreviation: eMSC, endometrial mesenchymal stem-like cells; Alpha 1; Acta, actin alpha; Col1a1, Collagen Type I; Fn1, Fibronectin