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Fig. 1 | Biological Research

Fig. 1

From: Lactadherin immunoblockade in small extracellular vesicles inhibits sEV-mediated increase of pro-metastatic capacities

Fig. 1

MFGE8 expression is associated with worse survival in BC advanced stages and more aggressive PAM50 subtypes. A Harmonized survival data from Liu et al. [59]⁠ was used to perform univariate survival analysis between advanced (stages III-IV) and early (stages I-II) BC patients, using progression-free interval as primary outcome, as recommended by TCGA. B Sub-analysis between advanced and early BC by PAM50 subtype was also performed. Samples were labeled as MFGE8-high and low using a median cutoff value. All survival analyses were conducted using RNA-seq UQ-FPKM values, through implementation of the survival and survminer R packages

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