Table 1 Evaluation of embryo morphological and ploidy between the Control and Mito ICSI group
| Â | Young | Old | ||||
|---|---|---|---|---|---|---|
Normal ICSI | Young source Mito ICSI | P-value | Normal ICSI | Old source Mito ICSI | P-value | |
Embryo morphological evaluation | ||||||
 No. of embryo screened | 21 | 21 |  | 15 | 14 |  |
 Rate of fertilization (2PN) at EDD1 (%) | 71.4 (15/21) | 76.2 (16/21) | 0.73 | 73.3 (11/15) | 71.4 (10/14) | 0.62 |
 Rate of good-quality embryos at EDD3 (%) | 4.8 (1/21) | 9.5 (2/21) | 0.55 | 20.0 (3/15) | 42.9 (6/14) | 0.18 |
 Rate of 7–10 cell embryos at EDD3 (%) | 9.5 (2/21) | 23.8 (5/21) | 0.21 | 26.7 (4/15) | 50.0 (7/14) | 0.18 |
 Rate of blastocyst formation at EDD5 (%) | 9.5 (2/21) | 4.8 (1/21) | 0.55 | 13.3 (2/15) | 21.4 (3/14) | 0.47 |
 Rate of good-quality blastocyst at EDD5 (%) | 0.0 (0/21) | 0.0 (0/21) | – | 0.0 (0/15) | 7.1 (1/14) | 0.48 |
Embryo ploidy detection | ||||||
 No. of embryo screened | 10 | 8 |  | 7 | 9 |  |
 Detection rates (%) | 50.0 (5/10) | 50.0 (4/8) | 0.68 | 42.9 (3/7) | 77.8 (7/9) | 0.18 |
 Euploid (%) | 0.0 (0/5) | 0.0 (0/4) | – | 0.0 (0/3) | 28.6 (2/7) | 0.47 |
Aneuploid (%) | ||||||
 Segmental aneuploidy (≥ 10 Mbp) (%) | 20.0 (1/5) | 25.0 (1/4) | 0.72 | 33.3 (1/3) | 14.3 (1/7) | 0.53 |
 Complex aneuploidy (≥ 3 variations) (%) | 60.0 (3/5) | 75.0 (3/4) | 0.60 | 66.7 (2/3) | 57.1 (4/7) | 0.67 |
 Trisomy (%) | 0.0 (0/5) | 0.0 (0/4) | – | 0.0 (0/3) | 0.0 (0/7) | – |
 Monosomy (%) | 0.0 (0/5) | 0.0 (0/4) | – | 0.0 (0/3) | 0.0 (0/7) | – |
 Mosaic (%) | 20.0 (1/5) | 0.0 (0/4) | 0.56 | 0.0 (0/3) | 0.0 (0/7) | – |