Two murine models of sepsis: immunopathological differences between the sexes—possible role of TGFβ1 in female resistance to endotoxemia

Table 1 Determination of CFU, LPS and IgM in in Endotoxemia or CLP models

Analyte	Normal Median (Min–Max)		ExSh Median (Min–Max)		CLP Median (Min–Max)
Analyte	Male	Female	Male	Female	Male	Female
CFU/mL	–	–	–	–	39 (0–1100)	0 (0–80)
LPS (EU/mL)	0.264 (0.19–0.33)	0.175 ( 0.17–0.22)	1.934 (1.19–1.94)*	1.932 (1.83–2.03) *	0.25 (0.13–0.43)	0.379 (0.02–0.05)
IgM (OD)	0.49 (0.27–0.74)	0.27 (0.25–0.50)	0.039 (0.03–0.06)**	0.04 (0.04–0.08)	0.17 (0.10–0.21)+	0.11 (0.08–0.12)

CFU (Colony-forming Unit), mL (mililiter), LPS (Lipopolysaccharide), EU (Endotoxin Unit), IgM (Immunoglobulin M), OD (Optical Density). Statistical differences were considered when *p < 0.05, **p < 0.005 vs Normal group or + p < 0.05 vs ExSh Male. N = 6–7 mice per group to CFU. N = 4–5 mice per group to LPS. N = 4–5 mice per group to IgM

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