Fig. 8

The protein expression of ACE2 (a), Mas receptor (b) eNOS (c) nNOS (d), iNOS (e), CSE (f) and CBS (g) in left ventricle isolated form spontaneously hypertensive rats (SHR, n = 8), spontaneously hypertensive rats treated by MLN-4760 (SHR + MLN, n = 8), spontaneously hypertensive rats treated by zofenopril (SHR + ZOFE, n = 8), spontaneously hypertensive rats treated by MLN-4760 and zofenopril (SHR + MLN + ZOFE, n = 8). The results are presented as the mean ± S.E.M., and differences between groups were analyzed by two-way ANOVA, * p < 0.05, ** p < 0.01, *** p < 0.001 vs. SHR, ⁺⁺ p < 0.01, ⁺⁺⁺ p < 0.001 vs. SHR + MLN, ^§ p < 0.05, ^§§ p < 0.01 vs. SHR + ZOFE